Risk factors of deep vein thrombosis in children with osteomyelitis

Figures & data

Table 1. Patients’ demographic characteristics.

	DVT^a	NO DVT	p Value^#
Age
Mean age (months)	96.51 ± 18.98	85.51 ± 11.53	.39
Gender
Male	7	18	.69
Female	2	9
Thrombus sites
Femoral vein	8
Popliteal vein	6
Iliac vein	4
Posterior tibial vein	2
Anterior tibial vein	1
Clinical features
Pain	10
Swelling	8
Chest pain and dyspnoea	3

^a DVT: deep venous thrombosis.

^# p < .05 was statistically significant.

Table 2. Univariate analysis of risk factors for thrombosis in children with osteomyelitis.

Risk factors	Number	DVT^a (n = 9)	No DVT^a (n = 27)	p Value^#
Male	25	7	18	.69
WBC	–	6.10 (3.52–10.61)	6.92 (5.33–9.84)	.41
CRP	–	18 (5.5–54.5)	4 (3.0–31.0)	.41
Median age (months)	–	125 (29.5–150.0)	109 (25.5–140.0)	.39
ESR	–	54 (34.5–100.0)	34 (22–64)	.19
Surgery	23	3	20	.046
ICU staying	4	3	1	.041
Sepsis	17	7	10	.055
D-dimer	–	2.34 (1.32–8.09)	1.07 (0.6–2.3)	.027
Temperature	–	39.8 (38.75–40)	37 (36.9–39.5)	.019
MRSA	7	6	1	.000

^a DVT: deep venous thrombosis.

^# p < .05 was statistically significant.

Table 3. Logistic regression analysis of risk factors for thrombosis in children with osteomyelitis.

Risk factors	B	S.E.	Wald	p^#	Exp(B)	95%CI
MRSA	6.253	3.042	4.225	.04	519.4	1.337–201736.767
ICU	0.735	2.465	0.089	.766	2.084	0.017–261.201
Surgery	−0.137	1.796	0.006	.939	0.872	0.026–29.426
D-dimer	−0.464	0.337	1.888	.169	0.629	0.325–1.219
Sepsis	−4.172	3.403	1.503	.22	0.015	0–12.158
Temperature	−1.319	0.767	2.959	.085	0.267	0.059–1.202

CI: confidence interval; MRSA: methicillin-resistant Staphylococcus aureus.

^# p < .05 was statistically significant.

Data availability statement

All data generated or analysed during this study are included in this article. Further enquiries can be directed to the corresponding author.