The early use of inhaled nitric oxide in premature infants requiring respiratory support

Figures & data

Table 1. Details of response rate, time to response and duration of iNO treatment for patients in two recently published studies.

Parameter	Japanese study	PaTTerN registry study
Age of infants during iNO administration	Initiation of iNO during the first week	Use of iNO during the first week
GA of premature infants, mean (SD)	27.1 (3.5) weeks	29.4 (2.1) weeks
BW of preterm infants, mean (SD)	1043 (593) grams	1324 (481) grams
Overall response rate for term/late preterm	61%	88.2%
Overall response rate for preterm infants	59%	90%
Response time for preterm infants, mean (SD)	9.2 (15.0) hours	10.3 hours
Response time for term/late preterm infants, mean (SD)	12.9 (33.4) hours	15.4 hours
Response time for preterm infants, median	1 hour^Table Footnotea	5.1 hours
Duration of treatment for term/late preterm infants, mean (SD)	6.0 (12.3) days	6.2 (2.9) days
Duration of treatment for preterm infants, mean	3.5 (5.5) days	8.2 (9.1) days

GA: gestational age; BW: birth weight; iNO: inhaled nitric oxide; SD: standard deviation.

^a This is the median response time for all patients; the median response time for preterm infants is not provided separately.

Data availability statement

Data sharing is not applicable to this article as no new data were collected or analysed.