Calcium, phosphorus, magnesium levels in frequent respiratory tract infections

Figures & data

Table 1. Baseline characteristics of the recruited subjects.

Participants groups	N	Age (yeaes)	Boy (n)
Type of disease
Upper respiratory tract infections	41	5.97 ± 3.01	22
Bronchitis	33	4.62 ± 2.63	16
Ordinary pneumonia	111	4.89 ± 2.44	52
Severe pneumonia	28	3.85 ± 2.25	17
Type of pathogen infected
EB virus	49	4.69 ± 2.65	23
Herpes simplex virus	21	5.50 ± 3.83	15
Parainfluenza virus	14	5.00 ± 2.96	9
Influenza A virus	23	4.15 ± 1.99	12
Influenza B virus	31	5.32 ± 2.31	15
Cytomegalovirus	11	3.25 ± 2.87	7
Coxsackie virus	10	4.50 ± 2.84	6
Chlamydia	11	8.27 ± 2.05	5
Mycoplasma	113	5.39 ± 2.66	65
Single pathogen infected	85	5.11 ± 2.74	47
Two pathogens infected	57	5.12 ± 2.52	32
Three pathogens infected	23	5.15 ± 2.19	17
Four and more than four pathogens infected	17	6.57 ± 4.28	11
Normal controls	33	4.05 ± 1.63	17

Table 2. Correlation between Ca/P/Mg status and WBC/ESR/PLT/PCT in cases with respiratory diseases.

Index	Index	R	P
Ca	WBC	0.183	0.006
Ca	ESR	0.063	0.354
Ca	PLT	0.239	<10^-4
Ca	PCT	−0.193	0.004
P	WBC	−0.103	0.131
P	ESR	−0.163	0.018
P	PLT	0.059	0.389
P	PCT	−0.242	<10^-4
Mg	WBC	0.058	0.393
Mg	ESR	0.088	0.203
Mg	PLT	−0.094	0.167
Mg	PCT	−0.032	0.640

WBC: white blood cell; ESR: erythrocyte sedimentation rate; PLT: platelet; Ca: calcium; P: phosphorus, Mg: magnesium; PCT: procalcitonin.

Figure 1. Differences of serum Ca level between various FRTI groups and controls.

Figure 2. Differences of serum P level between various FRTI groups and controls.

Figure 3. Differences of serum Mg level between various FRTI groups and controls.

Figure 4. Serum Ca status among different participant groups (Ca status: mmol/L).

Table 3. Characteristics of Ca/P/Mg levels in respiratory .diseas es.

Subjects	Ca	P	Mg
Upper respiratory tract infections	2.33 ± 0.12	1.38 ± 0.27	0.94 ± 0.07
Bronchitis	2.37 ± 0.08	1.46 ± 0.20	0.96 ± 0.07
Ordinary pneumonia	2.31 ± 0.10	1.36 ± 0.24	0.96 ± 0.07
Severe pneumonia	2.31 ± 0.14	1.34 ± 0.27	0.93 ± 0.07
Type of pathogen infected
EB virus	2.33 ± 0.10	1.35 ± 0.24	0.93 ± 0.07
Herpes simplex virus	2.34 ± 0.07	1.35 ± 0.11	0.97 ± 0.07
Parainfluenza virus	2.37 ± 0.11	1.43 ± 0.17	0.94 ± 0.05
Influenza A virus	2.27 ± 0.15	1.18 ± 0.33	0.96 ± 0.06
Influenza B virus	2.36 ± 0.12	1.39 ± 0.25	0.94 ± 0.07
Cytomegalovirus	2.38 ± 0.13	1.54 ± 0.46	0.96 ± 0.06
Coxsackie virus	2.27 ± 0.11	1.26 ± 0.18	0.97 ± 0.08
Chlamydia	2.36 ± 0.12	1.52 ± 0.27	0.94 ± 0.06
Mycoplasma	2.33 ± 0.11	1.36 ± 0.24	0.95 ± 0.06
Single pathogen infected	2.32 ± 0.11	1.39 ± 0.27	0.95 ± 0.08
Two pathogens infected	2.35 ± 0.12	1.37 ± 0.24	0.94 ± 0.06
Three pathogens infected	2.34 ± 0.10	1.31 ± 0.27	0.97 ± 0.06
Four and more than four pathogens infected	2.30 ± 0.10	1.30 ± 0.17	0.95 ± 0.05
Normal controls	2.29 ± 0.11	1.34 ± 0.30	0.95 ± 0.07

HSPN: Ca: calcium; P:phosphorus; Mg: magnesium.

Figure 5. Serum Ca level ROC curve for bronchitis (AUC = 0.282).

Figure 6. Serum Ca level ROC curve for parainfluenza virus infection (AUC = 0.310).

Figure 7. Serum Ca level ROC curve for influenza B virus infection (AUC = 0.330).

Figure 8. Serum Ca level ROC curve for cytomegalovirus infection (AUC = 0.312).

Table 4. Association between Ca level and respiratory diseases.

Index	ROC area	95% CI	p	Cut-off point
Bronchitis	0.282	0.087–0.478	0.047	2.33
Parainfluenza virus	0.310	0.119–0.500	0.068	2.32
Influenza B virus	0.330	0.170–0.489	0.0499	2.33
Cytomegalovirus	0.312	−0.038–0.663	0.250	2.29

ROC: receiver operating characteristic curve.

Data availability statement

The data will be shared by the corresponding author upon the scientific request.