Health-related quality of life in patients with generalized pustular psoriasis – a Swedish register study

Figures & data

Table 1. Demographic and clinical characteristics of patients with generalized pustular psoriasis and plaque psoriasis at first observation in PsoReg.

	Plaque psoriasisa	GPPb	p Value
Number of patients	7041	80	–
Females	2635 (37)	54 (68)	<.01
Age, mean (SD)	50.7 (16.0)	53.9 (17.7)	<.05
BMI, kg/m^2, median (IQR)	27.5 (6.8)	27.6 (8.3)	.67
Waist, cm, median (IQR)	100.0 (20.0)	99.0 (21.0)	.325
Psoriasis onset age >30 years	2517 (36)	39 (49)	<.05
Current smoker	1575 (22)	14 (18)	.298
Risk consumption of alcoholc	651 (9)	4 (5)	.180
Plaque psoriasis	7041 (100)	15 (19)	–
Psoriatic arthritis	1151 (16)	11 (14)	.677
Nail psoriasis	1315 (19)	14 (18)	.788
Guttate psoriasis	188 (3)	3 (4)	.522
Non-pustular palmoplantar psoriasis	157 (2)	2 (3)	.700
Biologic treatmentd	1697 (24)	33 (41)	<.01
Non-biologic systemic treatment onlyd	4445 (63)	38 (48)	<.01

BMI: body mass index; GPP: generalized pustular psoriasis; IQR: interquartile range; PsoReg: Swedish National Register for Systemic Treatment of Psoriasis; SD: standard deviation.

Data are n (%) unless stated otherwise.

^a Patients with plaque psoriasis and no GPP.

^b Patients with GPP, with or without concomitant plaque psoriasis.

^c High-risk intake in accordance with the Swedish National Board of Health and Welfare definition.[26].

^d Treatment at the first observation for each patient in PsoReg.

Figure 1. Box plots and descriptive statistics showing HRQoL by (A) EQ-5D and (B) DLQI scores in patients with plaque psoriasis or GPP. The centre line in each box represents the median; box limits represent the IQR; whiskers represent 1.5 × the IQR and black circles represent outliers. DLQI: Dermatology Life Quality Index; EQ-5D: EuroQol-5 Dimensions; GPP: generalized pustular psoriasis; HRQoL: health-related quality of life; IQR: interquartile range.

Figure 2. Degree of severity of total DLQI score in plaque psoriasis or GPP. DLQI: Dermatology Life Quality Index; GPP: generalized pustular psoriasis.

Figure 3. Proportion of patients with (A) plaque psoriasis or (B) GPP with each response level for the five dimensions of the EQ-5D. EQ-5D: EuroQol-5 Dimensions; GPP: generalized pustular psoriasis.

Figure 4. Proportion of patients with (A) plaque psoriasis or (B) GPP with each score for the individual health domains of the DLQI. DLQI: Dermatology Life Quality Index; GPP: generalized pustular psoriasis.

Swedish National Board of Health and Welfare. Rådgivande samtal om alkohol [Advisory conversation on alcohol]; 2015. Available from: https://www.socialstyrelsen.se/globalassets/sharepoint-dokument/artikelkatalog/ovrigt/2015-1-8.pdf2015

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Data availability statement

The data that support the findings of this study were retrieved from PsoReg. Restrictions apply to the availability of these data under Swedish and European law, which were used under license for the current study, and so are not publicly available.