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Original Articles

Antihypertensive therapy prevents new-onset atrial fibrillation in patients with isolated systolic hypertension: the LIFE study

, , , , , & show all
Pages 317-326 | Received 05 Mar 2019, Accepted 16 Jun 2019, Published online: 01 Jul 2019

Figures & data

Table 1. Baseline demographic and clinical characteristics in relation to new-onset atrial fibrillation in 1248 patients with isolated systolic hypertension.

Table 2. Predictors of new-onset atrial fibrillation in 1248 patients with isolated systolic hypertension.

Figure 1. Flow chart of the patients who participated in the present study.

Figure 1. Flow chart of the patients who participated in the present study.

Figure 2. Development of systolic blood pressure (, upper panel) and diastolic blood pressure (, lower panel) in the ISH patients and the non-ISH patients who had incident AF and the patients who did not have incident AF. The y-axes have been truncated.

Figure 2. Development of systolic blood pressure (Figure 2a, upper panel) and diastolic blood pressure (Figure 2b, lower panel) in the ISH patients and the non-ISH patients who had incident AF and the patients who did not have incident AF. The y-axes have been truncated.

Figure 3. Cornell product as indicator of ECG-LVH at baseline and yearly during the study in the ISH patients and the non-ISH patients with new-onset AF (upper lines) and in patients without new-onset AF during the study (lower lines). The y-axis has been truncated.

Figure 3. Cornell product as indicator of ECG-LVH at baseline and yearly during the study in the ISH patients and the non-ISH patients with new-onset AF (upper lines) and in patients without new-onset AF during the study (lower lines). The y-axis has been truncated.

Table 3. Predictors of new-onset atrial fibrillation in 7583 patients with non-isolated systolic hypertension.

Table 4. Time dependent (time to event) multivariate Cox regression analyses to assess the risk of incident atrial fibrillation related to in-treatment variation of 10 mmHg in systolic BP in patients with isolated systolic hypertension and non- isolated systolic hypertension.

Table 5. Time dependent (time to event) multivariate Cox regression analyses to assess the risk of the combined end point of incident atrial fibrillation or all-cause mortality related to in-treatment variation of 10 mmHg in systolic BP in patients with isolated systolic hypertension and non-isolated systolic hypertension.

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