Hypertension in older patients: a STEP forward?

Figures & data

  

Table 1. Selected exclusion criteria in the STEP study which are relevant in older patients.

Individuals older than 80 years.

SBP ≥190 mmHg, or diastolic blood pressure (DBP) <60 mmHg).

History of large atherosclerotic cerebral infarction or haemorrhagic stroke (not including lacunar infarction and transient ischaemic attack [TIA]).

Hospitalisation for Myocardial Infarction or unstable angina within the last 6 months.

Coronary revascularization (percutaneous coronary intervention [PCI] or coronary artery bypass grafting [CABG]) within the last 12 months.

Planned to perform coronary revascularization (PCI or CABG) in the next 12 months.

History of sustained Atrial Fibrillation.

New York Heart Association (NYHA) class III–IV heart failure or hospitalisation for exacerbation of chronic heart failure.

Severe valvular disease or valvular disease likely to require surgery or percutaneous valve replacement during the trial.

Uncontrolled diabetes mellitus (serum fasting glucose ≥200 mg/dL [11.1 mmol/L], HbA1 > 8%).

Estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m^2, or serum creatinine >2.5 mg/dL [>221 µmol/L]).

Severe somatic disease such as cancer.

Severe cognitive impairment or mental disorders.