Development of Hypertension in a Pyelonephritis-Induced Model: The Effect of Salt Intake and Inability of Renal Sodium Handling

Figures & data

Figure 1 Systolic blood pressure (SBP), creatinine clearance (C_Cr), fractional sodium (FE_Na), potassium excretion (FE_K), and proximal (FEP_Na) and post-proximal (FEPP_Na) fractional sodium excretion for all experimental groups. The data are reported as the means ± SEM. *p value ≤ 0.05 was considered to indicate statistical significance between experimental groups over time data (ANOVA and Bonferroni's contrast test).

Table 1 Body weight as related to age, sodium intake, serum sodium, potassium, and lithium data for all experimental groups fed a standard diet

Groups (n)	Na^+(mM)	K^+(mM)	Li^+(mM)	21-d	Body weight (g)28-d	35-d	Sodium intake(mmol/wk/100 g
CO (8)	139±1.5	3.6±0.1	0.17±0.001	315±10			14.1±2.5
COs (9)	139±2.6	4.0±0.2	0.20±0.004		308±8		12.9±2.3
COs+UNx (7)	136±2.0	3.4±0.1	0.20±0.001			304±9	12.3±2.1
CP (11)	137±1.2	3.6±0.1	0.12±0.001	334±12			13.8±1.7
CPw (7)	142±1.1	4.2±0.2	0.18±0.002		304±12		15.9±2.2
CPw+UNx (8)	140±2.2	3.5±0.1	0.25±0.002			306±11	14.4±2.6
CPs (7)	142±3.5	3.7±0.1	0.18±0.001		347±15		14.9±2.1
CPs+UNx (8)	142±2.0	4.0±0.1	0.19±0.001			340±12	13.3±1.7

Data are reported as the means ± SEM.