A Comparison of Sevelamer Hydrochloride with Calcium Acetate on Biomarkers of Bone Turnover in Hemodialysis Patients

Figures & data

Table 1 Baseline demographic and background characteristics

Characteristic	All group (N = 70)	Sevelamer (N = 37)	Calcium acetate (N = 33)	p value
Sex
Male	38	21	17	0.651
Female	32	16	16
Age (years)	48.9 ± 11.5	47.6 ± 11.9	50.4 ± 10.9	0.260
Weight (kg)	58.2 ± 9.6	59.7 ± 10.4	56.6 ± 8.5	0.238
Primary cause of ESRD
Hypertension	21	11	10	0.810
Diabetes nephropathy	8	3	5
Polycystic kidneys	2	1	1
Others (including CGN)	39	22	17
Dialysis duration (years)	7.3 ± 5.5	7.3 ± 6.1	7.4 ± 4.8	0.783
Type of phosphate binders
Calcium carbonate	39	19	20	0.556
Calcium acetate	31	18	13
Parathyroidectomy
No	66	35	31	0.947
Yes	4	2	2
Kt/V	1.5 ± 0.4	1.6 ± 0.5	1.4 ± 0.2	0.124

*Mean ± S.D.

Abbreviations: ESRD = End-stage renal disease; CGN: Chronic glomerulonephritis.

Figure 1 Serum intact parathyroid hormone (iPTH) level (Median, 25^th and 75^th percentile).

Figure 2 Serum alkaline phosphatase (Alk-P) level (mean ± SE).

Figure 3 Serum phosphorus level (mean ± SE).

Figure 4 Serum calcium × phosphorus (Ca × P) level (mean ± SE).

Figure 5 Serum calcium_[adj] level (mean ± SE).