Steroid Responsiveness of Children with Idiopathic Nephrotic Syndrome in Southeastern Region of Turkey

Figures & data

Table 1 Some clinical and laboratory findings of the patients with INS at first admission

	Mean ± SD	Median (min-max)
Initial age of NS (year)	4.8 ± 3.2	4 (0.9–15.0)
Total follow-up time (month)	35.6 ± 21.9	29 (12–96)
Initial proteinuria (mg/m^2/h)	117.7 ± 83.3	95 (40–539)
Serum albumin level (mg/dL)	1.6 ± 0.7	1.6 (0.5–4.1)
Serum cholesterol level (mg/dL)	378 ± 145	368 (97–760)
Number of infections developed	2.5 ± 2.0	2.0 (0–10)

Figure 1. Response rate of the patients with INS to steroid therapy in our study group.

Table 2 Comparison of steroid response and factors affecting this response

		Steroid response (n = 48), n (%)	Steroid-dependent (n = 19), n (%)	Steroid non-responder (n = 17), n (%)	Total	p
Hypertension	Existing	2 (4.2)	5 (26.4)	6 (35.3)	13	0.003
	Absent	46 (95.8)	14 (73.6)	11 (64.7)	71
Hematuria	Existing	5 (10.4)	4 (21.1)	11 (64.7)	20	<0.001
	Absent	43 (89.6)	15 (78.9)	6 (35.3)	64
Age	≥6 age	7 (14.6)	2 (10.5)	8 (47.1)	17	0.015
	≤6 age	41 (85.4)	17 (89.5)	9 (52.9)	67
Remission in the fifteenth day	Existing	33 (68.7)	5 (26.3)	1 (5.9)	39	<0.001
	Absent	15 (31.3)	14 (73.7)	16 (94.1)	45

Table 3 Remission rates of our patients in the first 15 days of the treatment

Remission in the fifteenth day	Patients with INS, n (%)
	MCNS	FSGS	DMP	Total	p
Yes	35 (66.5)	2 (8.2)	2 (8.2)	45	0.006
No	27 (43.5)	9 (81.8)	9 (81.8)	39	0.006

Abbreviations: MCNS = minimal change nephrotic syndrome, FSGS = focal segmental glomerulosclerosis, DMP = diffuse mesangial proliferation.