Figures & data
Table 1 Composition of diet (g/100 g)
Table 2 Changes in body weight, kidney weight, and urine volume of experimental animals
Table 3 Plasma glucose, insulin, and insulin sensitivity indices of experimental animals
Figure 1. Oral glucose tolerance test curves of experimental animals. Values are means ± SD (n = 6). CON: control rats; FRU: fructose-fed rats; FRU + GEN: fructose-fed rats treated with genistein (1mg/kg b.w); CON + GEN: control rats treated with genistein (1mg/kg b.w). asignificant at p < 0.05 compared to CON ANOVA followed by DMRT.
Table 4 Levels of urea, uric acid, creatinine, total protein, and albumin in plasma of experimental rats
Table 5 Urinary urea, uric acid, creatinine, and albumin of experimental animals
Table 6 Levels of sodium and potassium in plasma (mEq/L) and urine (mmol/L/day) of experimental animals
Table 7 Urea and creatinine clearance rate (ml/min) in experimental animals
Table 8 Levels of thiobarbituric reactive substances (TBARS) and reduced glutathione (GSH) in kidney of experimental rats
Figure 2. Histopathology of kidney using hematoxylin and eosin (A–G; H&E × 20). Control rats showed normal glomeruli and tubules (). represent kidney section of high-fructose-fed rats. shows tubules having fatty infiltration. shows segmented glomerulo nephritis, with the tubules showing fat accumulation. shows hyaline casts in tubules. shows fatty infiltration in parenchyma cells, and represents the kidney section of fructose-fed rats treated with genistein, showing cloudy swelling and mild fat accumulation in tubules. represents the kidney section of normal rats treated with genistein in which the glomeruli show mild congestion.
