Serum Neutrophil Gelatinase-Associated Lipocalin as a Marker of Renal Function in Non-Diabetic Patients with Stage 2–4 Chronic Kidney Disease

Figures & data

Table 1 Basal clinical and biochemical characteristics of the studied groups

	Healthy volunteers (n = 34)	eGFR, 60–89 ml/min (n = 52)	eGFR, 30–59 ml/min (n = 25)	eGFR, 15–29 ml/min (n = 15)
Age (years)	43.15 ± 16.05	43.97 ± 13.12	46.60 ± 12.06	48.10 ± 9.13
eGFR (mL/min)	108.67 ± 18.14	74.27 ± 8.12^‡	49.53 ± 7.84^‡	21.43 ± 6.54^‡
Creatinine (mg/dL)	0.77 ± 0.18	1.03 ± 0.19^‡	1.47 ± 0.87^‡	2.77 ± 1.14^‡
Ht (%)	42.67 ± 2.97	41.97 ± 5.03	39.44 ± 3.73^†	35.85 ± 5.48^‡
Hb (g/dL)	14.75 ± 2.67	14.06 ± 1.66	13.66 ± 1.29^†	11.48 ± 2.22^‡
Leukocyte count (× 10^3/L)	5.45 ± 1.95	6.87 ± 1.98	7.67 ± 1.85	8.53 ± 2.96^†
hsCRP (mg/mL)	0.31 ± 0.10	0.89 ± 0.98	2.16 ± 2.08^‡	3.77 ± 2.52^‡
Cholesterol (mg/dL)	164.26 ± 38.25	188.20 ± 36.43	206.64 ± 39.44	179.80 ± 41.52
Serum NGAL (ng/mL)	76.34 ± 27.87	115.05 ± 40.03^†	154.19 ± 49.25^‡	258.19 ± 73.37^‡
Urinary NGAL (ng/mL)	5.98 ± 3.79	19.98 ± 13.17^†	36.18 ± 27.73^‡	79.85 ± 54.55^‡
Cystatin C (mg/L)	0.81 ± 0.19	1.24 ± 0.47	1.96 ± 1.28^†	3.14 ± 2.98^‡

Values given are means ± SD.

*p < 0.05, ^†p < 0.01, ^‡p < 0.001 vs. healthy volunteers.