Evaluation of sE-Selectin and sICAM-1 as Parameters for Renal Function

Figures & data

Table 1 Patients‘ biometric data, hemodynamics, score values, and operation and transfusion data

	Group 1: control group	Group 2: Acute renal failure
Number (n)	22	11
Age (years)	42.4 ± 15.4	53.2 ± 16.2
Sex (f/m)	5 f/17m	0 f/11m
Height (cm)	178.5 ± 6.6	173.7 ± 7.5
Weight (kg)	81.6 ± 8.6	73.3 ± 13.9
Body surface area (m^2)	1.90 ± 0.13	1.87 ± 0.20
Days in intensive care unit (median, range)	11–15 (14)	13–18 (16)
ARF	0	11
Mortality	13.6%	72.7%
Diagnosis
Head and brain trauma	11	5
Thorax trauma	7	6
Abdominal trauma	8	5
Extremity trauma	15	8
APACHE-II score
At admission	18	19
Maximum (day)	21 (6)	25 (7)
Mean arterial pressure (MAP) at admission (mmHg)	63	68
Central venous pressureat admission (mmHg)	6	7
Cause of death
Circulation arrest		3
Multiple organ failure		2
Number of operations (median, range)	2 (1–6)	2 (0–7)
Number of blood products (median, range)	4 (3–18)	5 (3–20)
Colloidal infusion (number of patients)	16	10
Antibiotic therapy (number of patients)	22	11
Aminoglycosides	2	3

*significant difference between the groups, p < 0.05.

Figure 1. Changes of diuresis and urea in the study groups. (¹significant differences to the time of admission, ²significant differences between the groups, p < 0.05.)

Figure 2. Changes of creatinine in serum and creatinine clearance in the study groups. (¹significant differences to the time of admission, ²significant differences between the groups, p < 0.05.)

Figure 3. Changes in excretion of α1-microglobulin (α1-MG) and N-Acetyl-ß-D-Glucosaminidase (NAG). (¹significant differences to the time of admission, ²significant differences between the groups, p < 0.05.)

Figure 4. Changes in excretion of total protein. (¹significant differences to the time of admission, ²significant differences between the groups, p < 0.05.)

Figure 5. Changes of excretion of sICAM-1 and sE-Selectin in urine. (¹significant differences to the time of admission, ²significant differences between the groups, p < 0.05.)