Coronary artery bypass grafting vs. drug-eluting stent implantation in patients with end-stage renal disease requiring dialysis

Figures & data

Table 1. Baseline characteristics based on treatment strategies^a.

	PCI (n = 86)	CABG (n = 26)	p Value
Male gender (% of patients)	67.4%	76.9%	.357
Age (years)	62.17 ± 11.30	63.65 ± 10.85	.556
Hypertension (%)	96.5%	96.2%	1.0
Diabetes mellitus (%)	54.7%	50.0%	.677
Current smoker (%)	11.8%	23.1%	.264
Previous MI (%)	23.3%	19.2%	.666
Previous PCI (%)	10.5%	7.7%	.968
Previous CABG (%)	1.2%	0%	1.0
Dialysis modality (% of hemodialysis)	54.7%	61.5%	.535
ACS (%)	87.2%	100%	.123
Body mass index	24.26 ± 3.67	24.37 ± 3.34	.797
One vessel disease (%)	15.1%	0%	.079
Two vessels disease (%)	24.4%	19.2%	.583
Three vessels disease (%)	60.5%	80.8%	.057
LM disease (%)	11.6%	57.7%	<.01
LVEF (%)	54.4 ± 14.5	56.9 ± 17.7	.524
Medical therapy
Aspirin (%)	91.9%	96.2%	.756
P2Y12 receptor inhibitor (%)	100%	26.9%	<.01
RAAS inhibitor (%)	41.9%	15.4%	.014
β blocker (%)	84.9%	84.6%	1.0
Statin (%)	91.9%	46.2%	<.01

ACS: acute coronary syndrome; CABG: coronary artery bypass graft; MI: myocardial infarction; LM: left main; LVEF: left ventricle ejection fraction; RAAS: renin–angiotensin–aldosterone system.

a Data presented as percent or as the mean value ± SD.

Figure 1. Overall survival between CABG and PCI.

Figure 2. MACE-free survival between CABG and PCI.

Figure 3. Survival between different dialysis modality.

Table 2. Multivariate Cox regression of mortality^a.

Exposure	Univariate	Multivariate
Revascularization method
PCI	1.0	1.0
CABG	1.34 (0.71, 2.53) .37	1.65 (0.51, 5.31) .40
Age
<65	1.0	1.0
≥65	3.19 (1.77, 5.74) <.01*	2.87 (1.20, 6.85) .02*
Gender
Male	1.0	1.0
Female	1.49 (0.83, 2.67) .18	1.27 (0.51, 3.16) .61
BMI	1.12 (1.03, 1.22) .01	1.06 (0.96, 1.18) .25
Diabetes
No	1.0	1.0
Yes	1.01 (0.57, 1.78) .98	0.61 (0.25, 1.51) .29
Current smoker
No	1.0	1.0
Yes	0.63 (0.25, 1.60) .33	1.07 (0.35, 3.28) .90
Dialysis modality
Hemodialysis	1.0	1.0
Peritoneal dialysis	2.12 (1.19, 3.77) .01*	6.69 (2.35, 19.05) <.01*
Diseased vessel no.
One	1.0	1.0
Two	0.72 (0.26, 1.99) .52	1.30 (0.31, 5.41) .72
Three	0.79 (0.33, 1.91) .61	1.24 (0.32, 4.75) .76
Presence of LM disease
No	1.0	1.0
Yes	1.41 (0.74, 2.67) .30	2.27 (0.67, 7.63) .19
LVEF
≥50%	1.0	1.0
<50%	1.23 (0.68, 2.24) .49	0.91 (0.38, 2.22) .84

HD: hemodialysis; LM: left main; LVEF: left ventricle ejection fraction; PD: peritoneal dialysis.

a Data: HR (95% CI) p value.

* p<.05.