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Clinical Study

Proton pump inhibitor usage is associated with higher all-cause mortality and CV events in peritoneal dialysis patients

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Pages 398-405 | Received 05 Jul 2021, Accepted 09 Feb 2022, Published online: 02 Mar 2022

Figures & data

Figure 1. Flow chart including patient enrollment and outcomes.

Figure 1. Flow chart including patient enrollment and outcomes.

Table 1. Patient demographic and clinical characteristics.

Table 2. Significant risk factors for all-cause mortality and CV events.

Figure 2. Cumulative incidence curves for mortality and CV events by category of the use of PPI. (A) Cumulative incidence curves for all-cause mortality. (B) Cumulative incidence curves for the incidence of CV events. The curves were constructed using the Kaplan–Meier method and compared using the Mantel–Cox log-rank test.

Figure 2. Cumulative incidence curves for mortality and CV events by category of the use of PPI. (A) Cumulative incidence curves for all-cause mortality. (B) Cumulative incidence curves for the incidence of CV events. The curves were constructed using the Kaplan–Meier method and compared using the Mantel–Cox log-rank test.

Figure 3. Cumulative incidence curves for mortality and CV events by category of the usage of PPI after IPTW. (A) Cumulative incidence curves for all-cause survival. (B) Cumulative incidence curves for the incidence of CV events. The curves were constructed using the Kaplan–Meier method and compared using the Mantel–Cox log-rank test.

Figure 3. Cumulative incidence curves for mortality and CV events by category of the usage of PPI after IPTW. (A) Cumulative incidence curves for all-cause survival. (B) Cumulative incidence curves for the incidence of CV events. The curves were constructed using the Kaplan–Meier method and compared using the Mantel–Cox log-rank test.

Table 3. Relationship between PPI and the adverse prognosis.