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Renal Failure Volume 45, 2023 - Issue 1
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Clinical Study

The effects of timing onset and progression of AKI on the clinical outcomes in AKI patients with sepsis: a prospective multicenter cohort study

Meiping Wanga Department of Critical Care Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China;b Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University, Beijing, China;c Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, ChinaView further author information
,
Xia Wangb Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University, Beijing, ChinaView further author information
,
Bo Zhub Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University, Beijing, ChinaView further author information
,
Wen Lib Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University, Beijing, China;d Department of Critical Care Medicine, Peking University Third Hospital, Beijing, ChinaView further author information
,
Qi Jiangb Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University, Beijing, ChinaView further author information
,
Yingting Zuoc Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, ChinaView further author information
,
Jing Wenc Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, ChinaView further author information
,
Yan Hec Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, ChinaCorrespondence[email protected]
View further author information
,
Xiuming Xib Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University, Beijing, ChinaCorrespondence[email protected]
View further author information
&
Li Jianga Department of Critical Care Medicine, Xuanwu Hospital, Capital Medical University, Beijing, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2647-0380View further author information
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Article: 2138433 | Received 05 Jul 2022, Accepted 15 Oct 2022, Published online: 25 Apr 2023

Figures & data

Figure 1. Flowchart of participants included in the current study.

Figure 1. Flowchart of participants included in the current study.

Table 1. Baseline characteristics and outcomes of patients indifferent subgroups according to the timing onset and evolution of AKI.

Table 2. Clinical symptom and library values in subgroup patients according to the timing onset and evolution of AKI.

Figure 2. Sankey diagrams showing the severity of AKI by subgroups. (A)AKI onset; (B) AKI progression; (C) Combine AKI onset and evolution. AKI, acute kidney injury.

Figure 2. Sankey diagrams showing the severity of AKI by subgroups. (A)AKI onset; (B) AKI progression; (C) Combine AKI onset and evolution. AKI, acute kidney injury.

Figure 3. The association between AKI onset, evolution and clinical outcomes.

Figure 3. The association between AKI onset, evolution and clinical outcomes.

Table 3. Multivariate logistic regression analysis evaluating the risk factors on early persistent-AKI.

Supplemental material

Supplemental Material

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Data availability statement

The datasets generated and or analyzed during the current study are available from the corresponding author on reasonable request.

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