The intellectual base and global trends in contrast-induced acute kidney injury: a bibliometric analysis

Figures & data

Figure 1. Global characteristics of articles published on CI-AKI. (A) Number of articles issued per year. (B) Number of articles published by country/region. (C) Type of article and corresponding number of publications. (D) WoS catalog classification of research areas. (E) Funding status of the article. (F) The publisher of the article.

Figure 2. Flowchart of the screening process.

Figure 3. A network of national/regional and institutional cooperation in the field of CI-AKI. (A) The collaboration network of countries/regions. (B) The collaboration network of institutions.

Table 1. The top 10 countries/regions and institutions involved in CI-AKI.

Rank	Country/region	Counts	Centrality	Citations	Institution	Counts	Centrality	Citations
1	USA	1136 (24.54%)	0.56	49,621	Guangdong Acad Med Sci	82 (2.47%)	0.02	838
2	CHINA	711 (15.36%)	0.04	8898	Southern Med Univ	82 (2.47%)	0.01	930
3	ITALY	330 (7.13%)	0.15	13,620	Mayo Clin	59 (1.78%)	0.07	6610
4	TURKEY	294 (6.35%)	0.07	3557	Univ Michigan	52 (1.57%)	0.06	7342
5	GERMANY	205 (4.43%)	0.18	10,791	Univ Pittsburgh	52 (1.57%)	0.04	5466
6	JAPAN	194 (4.19%)	0.01	3340	Columbia Univ	51 (1.54%)	0.03	7338
7	UK	176 (3.80%)	0.16	10,370	Fujian Med Univ	44 (1.33%)	0.02	192
8	CANADA	146 (3.15%)	0.05	7280	Shanghai Jiao Tong Univ	43 (1.30%)	0.05	1700
9	SOUTH KOREA	114 (2.46%)	0.03	1932	Tianjin Med Univ	40 (1.21%)	0.01	473
10	AUSTRALIA	94 (2.03%)	0.04	4751	South China Univ Technol	37 (1.12%)	0	194

Figure 4. Visual analysis of journals. (A) The network of article source journals. (B) The network of cocited journals.

Table 2. The top 10 journals and cocited journals related to CI-AKI.

Rank	Journal	Counts	IF (2021)	JCR (2021)	Co-cited journal	Citations	IF (2021)	JCR (2021)
1	J AM COLL CARDIOL	297	27.203	Q1	J AM COLL CARDIOL	9288	27.203	Q1
2	EUR HEART J	224	35.855	Q1	CIRCULATION	6918	39.918	Q1
3	AM J CARDIOL	155	3.133	Q3	NEW ENGL J MED	6054	176.0774	Q1
4	ANGIOLOGY	141	3.299	Q3	KIDNEY INT	5794	18.998	Q1
5	CIRCULATION	135	39.918	Q1	AM J CARDIOL	5562	3.133	Q3
6	INT J CARDIOL	119	4.039	Q2	AM J KIDNEY DIS	3481	11.072	Q1
7	NEPHROL DIAL TRANSPL	112	7.186	Q1	J AM SOC NEPHROL	3431	14.978	Q1
8	CATHETER CARDIO INTE	90	2.585	Q3	RADIOLOGY	3277	29.146	Q1
9	JACC-CARDIOVASC INTE	53	11.075	Q1	JAMA-J AM MED ASSOC	3100	157.335	Q1
10	HEART	48	7.365	Q1	NEPHROL DIAL TRANSPL	2935	7.186	Q1

Figure 5. The dual-map overlay of journals.

Figure 6. Visual analysis of authors. (A) The collaboration network of scholars. (B) The network of cocited authors.

Table 3. The top 10 authors and cocited authors of CI-AKI research.

Rank	Author	Counts	Citations	Total link strength	Co-cited author	Citations	Total link strength
1	Liu, Y	147	1258	3752.63	Mccullough, PA	2316	2221.96
2	Chen, J	111	756	2904.12	Mehran, R	1773	1732.42
3	Tan, N	94	781	2178.73	Marenzi, G	1495	1414.22
4	Chen, S	81	384	2093.39	Briguori, C	1052	1024.21
5	Mehran, R	77	8257	3943.29	Solomon, R	925	907.02
6	Liu, J	64	250	1611.97	Rihal, CS	827	825.56
7	Mccullough, Pa	56	3525	2163.94	Barrett, BJ	695	680.33
8	Li, H	55	433	1452.4	Heyman, SN	683	652.55
9	Zhang, J	52	568	1429.84	Weisbord, SD	633	621.9
10	Li, Y	49	599	1434.82	Levey, AS	632	619.22

Table 4. The top 10 articles on CI-AKI.

Rank	Year	First author	Title	Total citations	Total link strength
1	2012	Khwaja [29]	KDIGO clinical practice guidelines for acute kidney injury	2134	4
2	2011	Levine [30]	2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions	2131	24
3	2004	Mehran [31]	A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: Development and initial validation	1633	65
4	2018	Aboyans [32]	2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)	1138	1
5	2013	Kellum [33]	Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1)	1102	3
6	2009	Kushner [34]	2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (updating the 2005 Guideline and 2007 Focused Update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines	1076	6
7	2009	Kushner [35]	2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines	1076	16
8	2007	Levin [36]	KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease	969	4
9	2011	Levine [30]	2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions	953	26
10	2012	Bellomo [37]	Acute kidney injury	923	9

Table 5. The top 10 cocited references of CI-AKI research.

Rank	Year	First author	Title	Local citations	Centrality
1	2004	Merten GJ [38]	Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial	170	0.09
2	2017	Nijssen EC [39]	Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomized, phase 3, controlled, open-label, non-inferiority trial	152	0.04
3	2007	Briguori C [40]	Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): a randomized comparison of 3 preventive strategies	139	0.02
4	2008	Mccullough PA [41]	Contrast-induced acute kidney injury	137	0.03
5	2006	Marenzi G [42]	N-Acetylcysteine and Contrast-Induced Nephropathy in Primary Angioplasty	133	0.04
6	2018	Weisbord SD [43]	Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine	132	0.04
7	2019	Mehran R [44]	Contrast-Associated Acute Kidney Injury	126	0.03
8	2003	Aspelin P [45]	Nephrotoxic effects in high-risk patients undergoing angiography	125	0.07
9	2011	Stacul F [46]	Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines	121	0.01
10	2004	Mehran R [31]	A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation	120	0.06

Figure 7. Visual analysis of cocited references. (A) Cluster analysis of cocited references. (B) The clustering timeline map of cocited references.

Table 6. The top 10 clusters of cocited references.

Cluster ID	Size	Silhouette	Label (LSI)	Label (LLR)	Label (MI)	Average year
0	118	0.935	Contrast-induced acute kidney injury	Contrast-associated acute kidney injury	Dehydration	2019
1	112	0.815	Contrast-induced nephropathy	Contrast-associated acute kidney injury	Dehydration	2014
2	79	0.881	Contrast-induced nephropathy	Acute renal failure	Dehydration	2004
3	71	0.88	Contrast-induced nephropathy	Practice guideline	Dehydration	2010
4	28	0.891	Contrast-induced nephropathy	Contrast-induced nephropathy	Pulmonary embolism	2006
5	27	0.968	Contrast-induced nephropathy	Renal function comparison	Contrast-induced nephropathy	1997
6	22	0.972	Acute kidney injury	Acute kidney injury	Contrast-induced nephropathy	2009
7	15	0.969	Renal function	Radiocontrast induced nephropathy	Contrast-induced nephropathy	2001
8	10	1	Contrast-induced nephrotoxicity—the effects of vasodilator therapy	Vasodilator therapy	Contrast-induced nephropathy	1993
9	8	1	Radiocontrast-associated renal dysfunction—a comparison of lower-osmolality and conventional high-osmolality contrast-media	Comparison	Contrast-induced nephropathy	1991

Figure 8. Visual analysis of keywords. (A) Heat map of keywords. (B) Cluster analysis of keywords. (C) The clustering timeline map of keywords.

Table 7. The top 20 keywords of CI-AKI research.

Rank	Keywords	Centrality	Counts	Year
1	contrast induced nephropathy	0.03	1151	2002
2	acute kidney injury	0.03	1097	2007
3	percutaneous coronary intervention	0.02	966	2003
4	acute renal failure	0.02	776	1992
5	contrast-induced nephropathy	0	752	2005
6	induced nephropathy	0.02	731	1994
7	risk	0.01	631	1991
8	prevention	0.01	603	2000
9	media	0.01	525	1991
10	angiography	0	456	1994
11	risk factor	0.01	435	1992
12	chronic kidney disease	0.01	392	2005
13	contrast media	0.01	380	1993
14	n acetylcysteine	0.01	376	2002
15	disease	0.01	373	2002
16	outcome	0.01	367	2004
17	coronary angiography	0.02	362	2004
18	mortality	0.01	333	2003
19	intervention	0.01	300	2003
20	impact	0	286	2005

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