Figures & data
Figure 2. Restricted-cubic-spline plot of the association between albumin to non-HDL-C ratio and all-cause mortality. The median albumin to non-HDL-C ratio was 10.8.
![Figure 2. Restricted-cubic-spline plot of the association between albumin to non-HDL-C ratio and all-cause mortality. The median albumin to non-HDL-C ratio was 10.8.](/cms/asset/5115dfa9-af9d-4e99-8396-b750ef4fe3d2/irnf_a_2299601_f0002_c.jpg)
Table 1. Baseline characteristics of the study population.
Figure 3. The Kaplan–Meier curves with all-cause mortality by category of the level of albumin to non-HDL-C ratio. The curves were constructed using the Kaplan–Meier method and compared using the Mantel-Cox log-rank test. Patients in the highest albumin to non-HDL-C ratio group (albumin to non-HDL-C ratio > 12.79) had a lower risk of all-cause mortality. Log-rank test of lowest vs. moderate, lowest vs. highest, and moderate vs. highest, was 24.35 (p < 0.001), 36.03 (p < 0.001), and 1.124 (p = 0.288), separately.
![Figure 3. The Kaplan–Meier curves with all-cause mortality by category of the level of albumin to non-HDL-C ratio. The curves were constructed using the Kaplan–Meier method and compared using the Mantel-Cox log-rank test. Patients in the highest albumin to non-HDL-C ratio group (albumin to non-HDL-C ratio > 12.79) had a lower risk of all-cause mortality. Log-rank test of lowest vs. moderate, lowest vs. highest, and moderate vs. highest, was 24.35 (p < 0.001), 36.03 (p < 0.001), and 1.124 (p = 0.288), separately.](/cms/asset/7e0d9eca-4593-48cd-8266-d94cfcd5de68/irnf_a_2299601_f0003_c.jpg)
Table 2. Albumin to non-HDL-C ratio predicts the prognosis of all-cause mortality in PD patients.
Figure 4. A: ROC curves of 3 indicators: albumin/non-HDL-C, non-HDL-C, albumin. The areas under the ROC curve (AUC) of albumin/non-HDL-C, non-HDL-C, albumin were 0.604 (p < 0.001), 0.583 (p < 0.001), and 0.552 (p < 0.001), respectively. B: ROC curves of 4 indicators: albumin/non-HDL-C, hs-CRP, BMI, and nPCR. The areas under the ROC curve (AUC) of albumin/non-HDL-C, hs-CRP, BMI, and nPCR were 0.523 (p = 0.123), 0.502 (p = 0.907), and 0.609 (p < 0.001), respectively.
![Figure 4. A: ROC curves of 3 indicators: albumin/non-HDL-C, non-HDL-C, albumin. The areas under the ROC curve (AUC) of albumin/non-HDL-C, non-HDL-C, albumin were 0.604 (p < 0.001), 0.583 (p < 0.001), and 0.552 (p < 0.001), respectively. B: ROC curves of 4 indicators: albumin/non-HDL-C, hs-CRP, BMI, and nPCR. The areas under the ROC curve (AUC) of albumin/non-HDL-C, hs-CRP, BMI, and nPCR were 0.523 (p = 0.123), 0.502 (p = 0.907), and 0.609 (p < 0.001), respectively.](/cms/asset/0388bcc0-d9b6-4816-b3fb-291fc951df67/irnf_a_2299601_f0004_c.jpg)
Figure 5. Competitive risk models. Estimated cumulative incidence curves between the all-cause mortality and other competing events for each albumin to non-HDL-C ratio group. The cumulative incidence curves for different albumin to non-HDL-C ratio groups are highly significant for the all-cause mortality (p < 0.001), while there is no statistical significance for the occurrence of other competing events (being transferred to hemodialysis therapy, being transferred to kidney transplantation, being transferred to other centers).
![Figure 5. Competitive risk models. Estimated cumulative incidence curves between the all-cause mortality and other competing events for each albumin to non-HDL-C ratio group. The cumulative incidence curves for different albumin to non-HDL-C ratio groups are highly significant for the all-cause mortality (p < 0.001), while there is no statistical significance for the occurrence of other competing events (being transferred to hemodialysis therapy, being transferred to kidney transplantation, being transferred to other centers).](/cms/asset/877ac20b-0a5c-446c-9405-821abe8654b5/irnf_a_2299601_f0005_c.jpg)
Figure 6. Sensitivity analyses. The whole cohort was categorized into four groups by the median values of non-HDL-C (3.25 mmol/L) and albumin (35.7 g/L). The repeated Kaplan-Meier curves showed the statistical significance of the association between the redefined groups and all-cause mortality (p < 0.001).
![Figure 6. Sensitivity analyses. The whole cohort was categorized into four groups by the median values of non-HDL-C (3.25 mmol/L) and albumin (35.7 g/L). The repeated Kaplan-Meier curves showed the statistical significance of the association between the redefined groups and all-cause mortality (p < 0.001).](/cms/asset/9de2f499-026b-4a12-a76c-1f7daa797c11/irnf_a_2299601_f0006_c.jpg)
Supplemental Material
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All data generated or analyzed during this study are included in this published article.