Figures & data
Table 1. Clinical characteristics of older adults with acute kidney injury in intensive care units.
Table 2. Risk factors associated with renal non-recovery among participants.
Figure 3. The predictive value of urinary biomarkers and the associated model. The ROC curves of urinary [TIMP-2]*[IGFBP7] and the associated model for predicting renal non-recovery from AKI. The AUC of using urinary [TIMP-2]*[IGFBP7] only, clinical prediction model only, and the [TIMP-2]*[IGFBP7] combined with clinical prediction model. ROC: receiver operating characteristic; AUC: area under the ROC.
![Figure 3. The predictive value of urinary biomarkers and the associated model. The ROC curves of urinary [TIMP-2]*[IGFBP7] and the associated model for predicting renal non-recovery from AKI. The AUC of using urinary [TIMP-2]*[IGFBP7] only, clinical prediction model only, and the [TIMP-2]*[IGFBP7] combined with clinical prediction model. ROC: receiver operating characteristic; AUC: area under the ROC.](/cms/asset/36221586-bb94-4a38-a6a9-2170839c392e/irnf_a_2304099_f0003_c.jpg)
Table 3. Biomarkers and combination models for predicting non-recovery from AKI.
Figure 4. The predictive value of biomarkers for 30-day mortality. The ROC curves of urinary [TIMP-2]*[IGFBP7] for predicting 30-day mortality after AKI. ROC: receiver operating characteristic; AUC: area under the ROC.
![Figure 4. The predictive value of biomarkers for 30-day mortality. The ROC curves of urinary [TIMP-2]*[IGFBP7] for predicting 30-day mortality after AKI. ROC: receiver operating characteristic; AUC: area under the ROC.](/cms/asset/9dba8a9d-b0c8-4bcc-be14-42686626ce1b/irnf_a_2304099_f0004_c.jpg)
Figure 5. Kaplan-Meier survival curves according to the cutoff value. Survival analysis regarding 30-day mortality using the Kaplan-Meier technique according to the cutoff value. (a) Survival curves of participants with urinary [TIMP-2]*[IGFBP7] ≥ 0.81 and those with < 0.81. (b) Survival curves of participants with high urinary [TIMP-2]*[IGFBP7] and high clinical risk model (≥ 0.50) and those with low clinical risk (< 0.50).
![Figure 5. Kaplan-Meier survival curves according to the cutoff value. Survival analysis regarding 30-day mortality using the Kaplan-Meier technique according to the cutoff value. (a) Survival curves of participants with urinary [TIMP-2]*[IGFBP7] ≥ 0.81 and those with < 0.81. (b) Survival curves of participants with high urinary [TIMP-2]*[IGFBP7] and high clinical risk model (≥ 0.50) and those with low clinical risk (< 0.50).](/cms/asset/de842f33-6557-4697-89c7-b5829b098be7/irnf_a_2304099_f0005_c.jpg)
Supplemental Material
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All data generated and/or analyzed during this study are included in this published article.