Joint Analysis of Health Histories, Physiological State, and Survival

Abstract

Data on individual health histories, age trajectories of physiological or biological variables, and mortality allow for the study of the joint evolution of health and physiological states and their effects on mortality. Individual health and physiological trajectories are described using a stochastic process with two mutually-dependent continuous and jumping components. The parameters of this process and mortality rate are identified from the data in which the continuous component is measured in discrete times, and transitions of jumping process are observed.

Keywords:

• aging related changes
• longitudinal data
• mortality modelling
• observational plans