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Original Articles

Lower proportion of CD19+IL-10+ and CD19+CD24+CD27+ but not CD1d+CD5+CD19+CD24+CD27+ IL-10+ B cells in children with autoimmune thyroid diseases

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Pages 46-55 | Received 11 Aug 2019, Accepted 22 Nov 2019, Published online: 02 Dec 2019

Figures & data

Table 1. Demographic and serological data of all 53 investigated patients.

Figure 2. Presentation of alterations in frequencies of different IL-10-producing B and regulatory B cells within total lymphocytes (A-D) and CD19+ B cells (E-H) in study groups including: CD19+IL-10+ (A, E), CD19+CD24+CD27+IL-10+ (B, F), CD1d+CD5+CD19+IL-10+ (C, G), CD1d+CD5+CD24+CD27+IL-10+ (D, H).

Figure 2. Presentation of alterations in frequencies of different IL-10-producing B and regulatory B cells within total lymphocytes (A-D) and CD19+ B cells (E-H) in study groups including: CD19+IL-10+ (A, E), CD19+CD24+CD27+IL-10+ (B, F), CD1d+CD5+CD19+IL-10+ (C, G), CD1d+CD5+CD24+CD27+IL-10+ (D, H).

Figure 3. Graphical presentation of changes in IL-10 production within total CD19+ B cells (A) and 3 different phenotypes of regulatory B cells: CD24+CD27+CD19+ (B); CD1d+CD5+CD19+ (C); CD1d+CD5+CD19+CD24+CD27+ (D).

Figure 3. Graphical presentation of changes in IL-10 production within total CD19+ B cells (A) and 3 different phenotypes of regulatory B cells: CD24+CD27+CD19+ (B); CD1d+CD5+CD19+ (C); CD1d+CD5+CD19+CD24+CD27+ (D).

Figure 4. Changes in percentage of putative phenotypes of regulatory B cells within lymphocytes (row above) and CD19+ B cells (row below) in study groups: CD19+CD24+CD27+ (A, D), CD1d+CD5+CD19+ (B, E), CD1d+CD5+CD24+CD27+CD19+ (C, F).

Figure 4. Changes in percentage of putative phenotypes of regulatory B cells within lymphocytes (row above) and CD19+ B cells (row below) in study groups: CD19+CD24+CD27+ (A, D), CD1d+CD5+CD19+ (B, E), CD1d+CD5+CD24+CD27+CD19+ (C, F).
Supplemental material

Supplementary_table_2.docx

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