Clinical Efficacy of Intraoperative Ultrasound for Prophylactic Lymphadenectomy of the Lateral Cervical Neck in Stage CN0 Papillary Thyroid Cancer: A Prospective Study

Figures & data

Table 1. Age and sex of 108 patients with papillary thyroid cancer (cases).

	Surgical + lymphatic dissection group (N = 57)			Surgical group (N = 51)
Age (y)	Male	Female		Male	Female		Total	χ^2	p
21–30	2	6		1	5		14	0.141	0.707
31–40	7	7		11	11		36	0.000	1.000
41–50	3	8		4	6		21	0.382	0.537
51–60	6	9		4	6		25	0.000	1.000
61–70	2	7		0	3		12	0.800	0.371

Table 2. Comparison of postoperative complication rates between the two groups (n,(%)).

	Cases (n)	Postoperative bleeding	Postoperative lymphatic leakage	Postoperative infection	Hypocalcemia	Postoperative hoarseness	Total incidence
Surgical + lymphatic dissection group	57	1 (1.75%)	1 (1.75%)	1(1.75%)	11 (19.30%)	7 (12.39%)	21(36.84%)
Surgical group	51	0 (0.00%)	0 (0.00%)	0(0.00%)	11 (21.57%)	3 (5.88%)	14 (27.45%)
χ^2		0.903	0.903	0.903	0.086	1.312	1.084
P		0.342	0.342	0.342	0.770	0.252	0.298

Table 3. Comparison of preoperative and 1 d postoperative parathyroid hormone and blood calcium levels in the two groups (mean ± SD).

		Parathyroid hormone(ng/L)		Serum calcium(mmol/L)
	Cases (n)	Preoperative	1 day postoperative	Preoperative	1 day postoperative
Surgical + lymphatic dissection group	57	40.39 ± 16.05	21.02 ± 10.74*	2.46 ± 0.11	2.06 ± 0.47*
Surgical group	51	40.79 ± 18.03	21.28 ± 12.29*	2.45 ± 0.17	2.30 ± 0.12*
t2
P		0.822	0.486	0.383	0.001

*P < 0.05 compared to preoperative.

Table 4. Recurrence of patients within 1 year after surgery in both groups (n,(%)).

Number of patients with recurrence	Cases (n)	Levels II, III and IV	Levels III and IV	Level IV	Total incidence
Surgical group	51	2(3.92%)	4(7.84%)	1(1.96%)	7(13.73%)
Surgical + lymphatic dissection group	57	0	0	0	0(0%)
χ2		2.277	4.643	1.128	8.366
P		0.131	0.031	0.288	0.003

Table 5. Relationship between lymph node metastasis in LCR and the number of lymph node metastasis in the central group.

	The number of lymph node metastasis in the central cervical region
	1	2	≥3
Total number of patients(n = 108)	49	21	38
Surgical group-LCR Lymph node metastasis rate(%)	7 (30%)	3 (30%)	7 (41%)
Surgical + lymphatic dissection group-LCR Lymph node metastasis rate (%)	3 (12%)	6 (55%)	8 (38%)
Total LCR Lymph node metastasis rate (%)	10 (20%)	9 (43%)	15 (40%)
χ2	4.607	1.744	1.033
p	0.032	0.182	0.309

LCR: the lateral cervical region.