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Review Article

Mini-Review: Tendon-Exposed Wound Treatments

, ORCID Icon &
Article: 2266758 | Received 19 Apr 2023, Accepted 28 Sep 2023, Published online: 09 Oct 2023

Figures & data

Figure 1. Pathophysiological mechanisms in the pathogenesis of tendon exposed wounds. The mechanisms include bacterial infection, poor vascularization, insufficient growth factors and lack of repair cells.

Figure 1. Pathophysiological mechanisms in the pathogenesis of tendon exposed wounds. The mechanisms include bacterial infection, poor vascularization, insufficient growth factors and lack of repair cells.

Figure 2. Mechanisms of PRP for tendon exposure wounds. PRP promotes the secretion of growth factors of PDGF, egf other growth factors. At the same time, it inhibits the inflammatory response and reduces the production of local ROS. Finally, these cytokines act on MSCs, macrophages fibroblasts, etc., and ultimately promote wound healing by means of inflammatory responses, proliferation and remodeling.

Figure 2. Mechanisms of PRP for tendon exposure wounds. PRP promotes the secretion of growth factors of PDGF, egf other growth factors. At the same time, it inhibits the inflammatory response and reduces the production of local ROS. Finally, these cytokines act on MSCs, macrophages fibroblasts, etc., and ultimately promote wound healing by means of inflammatory responses, proliferation and remodeling.

Figure 3. Treatment of tendon exposed wounds. Treatment options for exposed tendon wounds include: flap grafting, artificial skin combined with VSD, platelet rich plasma and other blood-related products, new dressings, and so on.

Figure 3. Treatment of tendon exposed wounds. Treatment options for exposed tendon wounds include: flap grafting, artificial skin combined with VSD, platelet rich plasma and other blood-related products, new dressings, and so on.

Data availability statement

All data used or analyzed during this study are included in this published article.