Figures & data
Table 1. Nominal deposited dose per session (NDDS) and the corresponding mixture concentrations in the pulmonary fluid for different propylene glycol/vegetable glycerin (PG/VG) ratios in the inhaled aerosolized e-liquid.
Figure 1. Definition of the mean surface tension (mean ST) and the surface tension amplitude (ST amplitude) in the experimental γ-A relationship (hysteresis loop).
![Figure 1. Definition of the mean surface tension (mean ST) and the surface tension amplitude (ST amplitude) in the experimental γ-A relationship (hysteresis loop).](/cms/asset/fc78dfb9-20ee-4c73-a2c5-3bd1214837fc/iiht_a_1478916_f0001_b.jpg)
Figure 2. Mean surface tension of lung surfactant (LS) in the presence of e-liquid mixture of various compositions and concentrations (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz). Dashed lines show the control range (pure LS).
![Figure 2. Mean surface tension of lung surfactant (LS) in the presence of e-liquid mixture of various compositions and concentrations (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz). Dashed lines show the control range (pure LS).](/cms/asset/409da879-14f6-4ca0-85f2-9d47d9d69378/iiht_a_1478916_f0002_b.jpg)
Figure 3. Amplitude of surface tension variations (amplitude ST) in the lung surfactant (LS) in the presence of e-liquid mixture of various compositions and concentrations (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz). Dashed lines show the control range (pure LS).
![Figure 3. Amplitude of surface tension variations (amplitude ST) in the lung surfactant (LS) in the presence of e-liquid mixture of various compositions and concentrations (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz). Dashed lines show the control range (pure LS).](/cms/asset/271ea30d-83a7-4c70-8b87-18cc65168c66/iiht_a_1478916_f0003_b.jpg)
Figure 4. Surface dilatational elasticity of the lung surfactant (LS) liquid interface in the presence of e-liquid mixtures of various compositions and concentrations (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz). Dashed lines show the control range (pure LS).
![Figure 4. Surface dilatational elasticity of the lung surfactant (LS) liquid interface in the presence of e-liquid mixtures of various compositions and concentrations (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz). Dashed lines show the control range (pure LS).](/cms/asset/64113a23-4b08-4176-8861-b867223aa405/iiht_a_1478916_f0004_b.jpg)
Figure 5. Surface dilatational viscosity of the lung surfactant (LS) liquid interface in the presence of e-liquid mixtures of various compositions and concentrations (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz). Dashed lines show the parameter range as in .
![Figure 5. Surface dilatational viscosity of the lung surfactant (LS) liquid interface in the presence of e-liquid mixtures of various compositions and concentrations (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz). Dashed lines show the parameter range as in Figures 2–4.](/cms/asset/5c2a3d24-f0b8-4757-b9c6-455bc172e6ca/iiht_a_1478916_f0005_b.jpg)
Figure 6. Total deviation (TDP) based on the combined deviations of three numerical parameters according to Equation (3) for e-liquids with different compositions and concentrations in the lung surfactant (LS) solution (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz).
![Figure 6. Total deviation (TDP) based on the combined deviations of three numerical parameters according to Equation (3) for e-liquids with different compositions and concentrations in the lung surfactant (LS) solution (NDDS – estimated nominal deposition dose per session). Data for the normal rate of breathing (0.25 Hz).](/cms/asset/f2ee3a85-fe36-4cdb-b93c-43d32e1944ed/iiht_a_1478916_f0006_b.jpg)