New horizons in clinical immunology: applications of induced pluripotent stem cells for the analysis of immune disorders

Figures & data

Table 1. Summary of immune cells derived from IPSCs.

Immune cells	iPS-cell-derived immune cell function	Reference
Dendritic cell	Antigen presentation	Choi et al. [11]
	Cytokine secretion	Senju et al. [12]
		Masakatsu et al. [13]
		IIzuka-Koga et al. [14]
Macrophage	Antigen presentation	Choi et al. [11]
	Phagocytosis	Senju et al. [12]
	Chemotaxis	Masakatsu et al. [13]
	Cytokine secretion (M1/M2)	Van Wilgenburg et al. [17]
Neutrophil	Phagocytosis	Choi et al. [11]
	Superoxide production
	Chemotaxis
NK cell	Cytokine secretion (interferon–γ)	Knorr et al. [18,19]
	Cytotoxic activity
NKT cell	Cytokine secretion (interferon–γ)	Kitayama et al. [20]
	Cytotoxic activity	Yamada et al. [21]
CD8+ T cell	Cytokine secretion (interferon–γ)	Nishimura et al. [22]
	Cytotoxic activity	Vizcardo et al. [23]

Figure 1. Application of human iPSCs for clinical immunology.

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