Figures & data
Fig. 1. HPLC profile of the extracts from A. oryzae transformant AO-ccsAC.
Fig. 2. HPLC profiles of the extracts from A. oryzae transformants; (i) AO-sol1; (ii) AO-sol1/2; (iii) AO-sol1/2/6; (iv) AO-sol1/2/6/5.
Fig. 3 Undesired oxidative transformation of prosolanapyrone I (6) in the AO-sol1/2.
Fig. 4. Undesired oxidations of fungal metabolites found in heterologous expression of biosynthetic gene clusters in A. oryzae.
Scheme 1. Proposed biosynthetic pathway of cytochalasin and undesired oxidation by A. oryzae.
Scheme 2. Reconstitution of solanapyrone biosynthetic gene cluster in A. oryzae.
Scheme 3. Undesired side reactions found in heterologous expression of biosynthetic gene clusters in A. oryzae.
Supplemental material
