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Bioscience, Biotechnology, and Biochemistry Volume 80, 2016 - Issue 4
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Food & Nutrition Science

Biological activities of unique isoflavones prepared from Apios americana Medik

Haruna KanetaDepartment of Food and Nutrition, Japan Women’s University, Tokyo, Japan
,
Mina KodaDepartment of Food and Nutrition, Japan Women’s University, Tokyo, Japan
,
Shun SaitoFaculty of Science and Technology, Department of Biosciences and Informatics, Keio University, Yokohama, Japan
,
Masaya ImotoFaculty of Science and Technology, Department of Biosciences and Informatics, Keio University, Yokohama, Japan
,
Manabu KawadaMicrobial Chemistry Research Foundation Institute of Microbial Chemistry (BIKAKEN), Numazu, Japan
,
Yoko YamazakiMicrobial Chemistry Research Foundation Institute of Microbial Chemistry (BIKAKEN), Numazu, Japan
,
Isao MomoseMicrobial Chemistry Research Foundation Institute of Microbial Chemistry (BIKAKEN), Numazu, Japan
&
Kazuoshi ShindoDepartment of Food and Nutrition, Japan Women’s University, Tokyo, JapanCorrespondence[email protected]
 show all
Pages 774-778 | Received 09 Sep 2015, Accepted 11 Nov 2015, Published online: 25 Jan 2016

Figures & data

Fig. 1. Structures of isoflavones (1–4) prepared from Apios americana Medik.

Fig. 1. Structures of isoflavones (1–4) prepared from Apios americana Medik.

Table 1. Estrogen receptor (ER) and androgen receptor (AR) binding activities of 1–4 (IC50 μM).

Fig. 2. ER agonistic activities (A) and antagonistic activities (B) of isoflavones.

Fig. 2. ER agonistic activities (A) and antagonistic activities (B) of isoflavones.

Table 2. Antioxidant activities of 1–4 (IC50 μM).

Table 3. α-glucosidase inhibitory activities of 1–4 (IC50 μM).

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