Coordinated process of polarized growth in filamentous fungi

Figures & data

Fig. 1. Scheme of tip growth in A. nidulans hyphae.

Notes: (A) Vesicle trafficking via the actin and microtubule cytoskeleton. Before fusion with the plasma membrane, secretion vesicles accumulate at Spitzenkörper. (B) MT-organizing center (MTOC) at spindle pole bodies and septa. Most MTs are oriented with their dynamic plus-ends towards the hyphal tip in the tip compartment.

Fig. 2. Relationship between polarity marker and exocytosis.

Notes: (A) Polarity markers determine polarity sites through the arrangement of actin cytoskeleton, vesicle transport and exocytosis. Polarity markers are delivered to the polarity site as cargo on secretory vesicles. (B) Active exocytosis may result in dilution or dispersion of the membrane-associated polarity markers.

Fig. 3. Transient polarity model. (adapted from [63]).

Notes: (A) Scheme of cell-end markers polarization and vesicle transport through actin and MT cytoskeleton. (B) Timelapse PALM of TeaR show the appearance of a new cluster (t = 5 s), a translational movement (t = 10 s) and a spreading of the signal along the plasma membrane. (C) Scheme of transient polarity model.