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Bioscience, Biotechnology, and Biochemistry Volume 81, 2017 - Issue 1
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Updated perspectives on the cytosolic sulfotransferases (SULTs) and SULT-mediated sulfation

Masahito SuikoFaculty of Agriculture, Department of Biochemistry and Applied Biosciences, University of Miyazaki, Miyazaki, JapanCorrespondence[email protected]
,
Katsuhisa KurogiFaculty of Agriculture, Department of Biochemistry and Applied Biosciences, University of Miyazaki, Miyazaki, Japan;Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, University of Toledo Health Science Campus, Toledo, OH, USA
,
Takuyu HashiguchiFaculty of Agriculture, Department of Biochemistry and Applied Biosciences, University of Miyazaki, Miyazaki, Japan
,
Yoichi SakakibaraFaculty of Agriculture, Department of Biochemistry and Applied Biosciences, University of Miyazaki, Miyazaki, Japan
&
Ming-Cheh LiuDepartment of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, University of Toledo Health Science Campus, Toledo, OH, USA
Pages 63-72 | Received 02 Jun 2016, Accepted 27 Jul 2016, Published online: 21 Sep 2016

Figures & data

Fig. 1. Typical SULT-mediated sulfation reactions.

Notes: Different SULT enzymes may catalyze the transfer of the sulfonate () group from the donor compound, PAPS, to the hydroxyl (−OH) or amino (−NH2) group of the substrate compound.
Fig. 1. Typical SULT-mediated sulfation reactions.

Fig. 2. Classification of the human and mouse SULTs based on their amino acid sequences.

Note: The dendrogram was generated based on the degree of amino acid sequences among the human and mouse SULTs.
Fig. 2. Classification of the human and mouse SULTs based on their amino acid sequences.

Fig. 3. Developmental stage-dependent expression of representative zebrafish SULTs.

Notes: Lanes 1 through 15 correspond to unfertilized zebrafish eggs, 0-, 1-, 3-, 6-, 12-, 24-, 48-, and 72-h zebrafish embryos, 1-, 2-, 3-, and 4-week-old zebrafish larvae, and 3-month-old male and female zebrafish.
Fig. 3. Developmental stage-dependent expression of representative zebrafish SULTs.

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Related Research Data

Sulfation of hesperetin, naringenin and apigenin by the human cytosolic sulfotransferases: a comprehensive analysis.
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