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Biochemistry & Molecular Biology

Imperatorin alleviates ROS-mediated airway remodeling by targeting the Nrf2/HO-1 signaling pathway

, , , , , , , , , & show all
Pages 898-910 | Received 17 Sep 2019, Accepted 20 Dec 2019, Published online: 03 Jan 2020

Figures & data

Figure 1. Effect of IMP on chronic airway inflammation, goblet cell hyperplasia, and collagen deposition.

Figure 1. Effect of IMP on chronic airway inflammation, goblet cell hyperplasia, and collagen deposition.

Figure 2. Effect of IMP on α-SMA and MMP-9 expression.

Figure 2. Effect of IMP on α-SMA and MMP-9 expression.

Figure 3. Effect of IMP on the production of ROS.

Figure 3. Effect of IMP on the production of ROS.

Figure 4. Effect of IMP on the expression of VEGF.

Figure 4. Effect of IMP on the expression of VEGF.

Figure 5. Effect of IMP on the expression of Nrf2, HO-1.

Figure 5. Effect of IMP on the expression of Nrf2, HO-1.

Figure 6. Effect of IMP on the nuclear translocation of NF-κB, phosphorylation of Akt, ERK, p38, and JNK.

Figure 6. Effect of IMP on the nuclear translocation of NF-κB, phosphorylation of Akt, ERK, p38, and JNK.
Supplemental material

Supplementary_Figure_1.pdf

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