Sesamin promotes angiogenesis and accelerates wound healing in rats via alleviates TBHP-induced apoptosis in human umbilical vein endothelial cells

Figures & data

Table 1. Primers used for real-time PCR analysis.

Genes	Forward primers	Reverse primers
Bcl-2	CCAGCGTATATCGGAATGTGG	CCATGTGATACCTGCTGAGAAG
Bax	CCCGAGAGGTCTTTTTCCGAG	CCAGCCCATGATGGTTCTGAT
CCASP3	AGAGGGGATCGTTGTAGAAGTC	ACAGTCCAGTTCTGTACCACG
β-actin	CTCGACACCAGGGCGTTATG	CCACTCCATGCTCGATAGGAT

Figure 1. Effects of sesamin on the cell viability of HUVEC.

Figure 2. Sesamin increased cell-matrix adhesion and attenuated cell-cell adhesion.

Figure 3. Sesamin enhanced migration and tube formation of HUVECs.

Figure 4. THBP induced cell apoptosis in HUVECs.

Figure 5. Sesamin alleviates TBHP-induced HUVECs apoptosis at gene level.

Figure 6. Sesamin alleviates TBHP-induced HUVECs apoptosis at protein level.

Figure 7. Sesamin inhibits TBHP-induced HUVECs apoptosis through caspase3 pathway.

Figure 8. Sesamin accelerated wound healing in rats.

Figure 9. Sesamin increased granulation thickness and enhanced collagen deposition and remodeling.

Data availability statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.