Suppression of NSDHL attenuates adipogenesis with a downregulation of LXR-SREBP1 pathway in 3T3-L1 cells

Figures & data

Figure 1. Knockdown of NSDHL decreased lipid accumulation in 3T3-L1 differentiated adipocytes.

Figure 2. Suppression of NSDHL decreased the expression of adipogenic genes in 3T3-L1 cells adipogenic program.

Figure 3. Impact of NSDHL knockdown during the MCE phase.

Figure 4. Interaction networks between NSDHL and eligible molecules.

Figure 5. Suppression of NSDHL in preadipocytes downregulated the pathway of LXR-SREBP1.

Figure 6. NSDHL knockdown increased 3T3-L1 preadipocytes proliferation.

Figure 7. Schematic overview of the proposed role of NSDHL in adipogenesis.

Data availability statement

The data described in this article are openly available in the Open Science Framework at DOI:10.17605/OSF.IO/TPA6U.