Tuberculin Skin Testing Induces Bilateral Tuberculous Uveitis in a Junior High School Student

ABSTRACT

We report a rare case of bilateral tuberculous uveitis associated with tuberculin skin testing (TST) in an otherwise healthy junior high school student. A 12-year-old boy presented with severely decreased vision in both eyes and a history of an intradermal PPD (purified protein derivative) skin test 12 days earlier. The best-corrected visual acuity (BCVA) was 20/1000 in both eyes (OU). Ocular examination showed multifocal grayish-yellow choroidal tubercles. Laboratory examinations, including T-SPOT.TB, revealed no abnormal findings. He was diagnosed with tuberculous uveitis. Combined corticosteriod and anti-tuberculosis therapy (ATT) was given. The BCVA improved to 20/25, and the choroidal tubercles faded away. Our case suggests that TST may induce bilateral uveitis in rare cases.

Declaration of Interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

DIsclaimer

The views expressed in the submitted article are our own and not an official position of the institution or funder.

Disclosure of Relationships and Activities

Huiying Zhao produced the first draft of the manuscript and figures. Xiaoyan Peng contributed to the study concept and design, and edited the manuscript, contributed to the final version sent for approval.

Additional information

Funding

Thanks to support by The Capital Health Research and Development of Special (No.SF-2018-2-1081).