ABSTRACT
Purpose
To describe the first case of varicella zoster virus (VZV) retinitis following chimeric antigenic response (CAR) T-cell therapy.
Methods
Case review.
Results
A 53-year-old male was treated with CAR T-cell therapy for refractory diffuse large B-cell lymphoma. Nine months after CAR T-cell therapy, he developed VZV skin infection and retinitis. The retinitis responded to systemic acyclovir therapy and intravitreal ganciclovir.
Conclusion
VZV retinitis can occur following CAR T-cell immunotherapy.
Declaration of interest
The authors declare no conflict of interest. The authors alone are responsible for the content and writing of the paper