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Original Articles

An electro-optic modulated heterodyne interferometer for measuring low glucose concentration

Pages 1899-1906 | Received 19 Jan 2009, Accepted 09 Oct 2009, Published online: 06 Nov 2009
 

Abstract

An electro-optic modulated heterodyne interferometer using the phase-lock technique for measuring the optical rotation angle corresponding to glucose concentration is presented. By inserting a half-wave plate behind the test sample and using the heterodyne interferometric phase-lock technique, it demonstrates a high sensitivity and is capable of measuring low glucose concentration. The validity of the proposed design is demonstrated by the measurements of rotation angles in a half-wave plate sample and the glucose sample, respectively. A correlation coefficient value of 0.999993 indicates a high linear response between the reference rotation angle and the measured rotation angle in a half-wave plate. Moreover, a standard deviation in rotation angle level of 5.9 × 10−4 has been obtained for glucose solutions with concentrations ranging from 0 to 1.2 g dl−1, with a correlation coefficient value of 0.99989 between the measured rotation angle and the glucose concentration. A standard deviation of rotation angle around 1.5 × 10−4 is achieved according to the repeatability experiments, and the relative error of rotation angle corresponding to the lowest measurable concentration of 0.01 g dl−1 has been determined to be 5.88%.

Acknowledgements

This research was supported by National Science Council of Taiwan Republic of China through contract number NSC-96-2622-E-269-026-CC3.

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