Comparison of the results of preimplantation genetic screening obtained by a-CGH and NGS methods from the same embryos

Figures & data

Table 1. Comparison of results using NGS and Agilent a-CGH.

# of embryo	a-CGH (Agilent)	NGS investigation	Amplification method
1	+10,+12,XY	+10,+12,XY	WGA-PCR
2	XX/XY mos	XX/XY mos	WGA-PCR
3	N,XY	N,XY	WGA-PCR
4	XX, +1 + 4 mos	XX, +1 + 4 mos (10–15%)	WGA-PCR
5	N,XX	N,XX	WGA-PCR
6	N,XX	N,XX	WGA-PCR
7	N,XX	N,XX	WGA-PCR
8	N,XX	N,XX	WGA-PCR
9	N,XX	N,XX	WGA-PCR
10	N,XY	N,XY	WGA-PCR
11	XXY	N,XY	WGA-PCR
12	+4,XY	+4,XY	WGA-PCR
13	N,XY	N,XY	WGA-PCR
14	XXY	N,XX	WGA-PCR
15	N,XY	N,XY	WGA-PCR
16	N,XY	N,XY	WGA-PCR
17	+16,XX (q arm)	+16,XX (q arm)	WGA-PCR
18	N,XX	N,XX	WGA-PCR
19	N,XX	N,XX	WGA-PCR
20	chaotic	chaotic	WGA-PCR
21 (rebiopsy of 9)	N,XX	N,XX	MDA
22 (rebiopsy of 10)	N,XY	N,XY	MDA
23 (rebiopsy of 13)	N,XY	N,XY	MDA
24 (rebiopsy of 15)	N,XY	N,XY	MDA
25	−16,XY	−16,XY	MDA
26	N,XY	N,XY	MDA
27	N,XY	N,XY	MDA
28	N,XY	N,XY	MDA
29	N,XY	N,XY	MDA
30	N,XY	N,XY	MDA
31	N,XX	N,XX	WGA-PCR
32	N,XX	N,XX	WGA-PCR
33	Chaotic	Chaotic	WGA-PCR
34	Chaotic	Chaotic	WGA-PCR
35	Chaotic	Chaotic	WGA-PCR
36	−13, +14, XY	−13, +14, XY	WGA-PCR
37	−19, −22, XY	−19, −22, XY	WGA-PCR
38	−15, −22, XY	−15, −22, XY	WGA-PCR

The results differ for a-CGH and NGS are highlighted in bold.