Figures & data
Figure 1. Computed Tomography Angiography (CTA) revealed embolization of the pulmonary trunk and its branches (indicated by the arrows).
Figure 2. Ultrasonography at the 14th week of gestation showed hypoechoic filling (A, arrow) of the superficial femoral vein, which could not be closed under pressure (B, arrow). Color Doppler ultrasound showed no color flow signal (indicated by the arrow) in the superficial femoral vein (C) or popliteal vein (D).
Figure 3. Genetic analysis of the PROC gene in the family. Sequencing of the PROC gene revealed that the patient carried the heterozygous deletion variant c.572_574delAGA of PROC. Family study showed that PROC c.572_574delAGA was inherited from the subject’s mother, while the subject’s brother did not inherit PROC c.572_574delAGA from his parents. The arrow indicates the mutation.
Figure 4. Schematic diagram of the possible mechanism of thrombus in this case.
Data availability statement
The data that support the findings of this study are available from corresponding author upon reasonable request.