Assessment of early vascular changes in adult females with polycystic ovary syndrome: correlation with insulin resistance

Figures & data

Table 1. CIMT of the PCOS group in comparison with control subjects.

	Cases					Control					P value
	Mean	SD	Median	Min	Max	Mean	SD	Median	Min	Max
CIMT	0.06	0.01	0.06	0.04	0.09	0.05	0.01	0.05	0.03	0.07	< 0.001

Table 2. Comparison of PCOS cases with insulin resistant and without insulin resistance regarding total cholesterol and LDL-C .

											P value
	With insulin resistant					Without insulin resistant
	Mean	SD	Median	Mini.	Maxi.	Mean	SD	Median	Mini.	Maxi.
T.cholesterol (mgldl)	201.14	37.67	191.00	135.00	295.00	173.68	33.34	172.50	112.00	260.00	0.009
LDL (mgldl)	132.82	34.91	129.00	74.00	213.00	107.85	34.68	111.50	14.00	188.00	0.015

Table 3. Correlation analysis with HOMA-IR and baseline demographic characteristics, metabolic and hormone profiles in the Polycystic Ovary Syndrome (PCOS) patients.

	HOMA-IR
	Pearson Correlation	Sig. (2-tailed)	N
HOMA-IR	1		50
Age	0.030	0.838	50
BMI	0.513	<0.001	50
waist circ	0.483	<0.001	50
SBP	0.415	0.003	50
DBP	0.310	0.029	50
TG	0.437	0.001	50
T.cholestrol	0.299	0.035	50
HDL	−0.280-	0.049	50
LDL	0.270	0.058	50
F.Testosterone	0.004	0.980	50

Table 4. Percentage of brachial artery diameter change 3 min after reactive hyperemia in PCOS group and control group.

	Cases					Control
	Mean	SD	Median	Mini.	Maxi.	Mean	SD	Median	Mini.	Maxi.	P value
%D change	10.20	9.86	7.00	0.00	41.00	20.60	10.54	17.50	5.00	39.00	< 0.001

Table 5. Linear regression with CIMT& ED as dependent variable and PCOS as independent predictor.

Model		Unstandardized Coefficients		Standardized Coefficients	t	P value	95.0% Confidence Interval for B
		B	Std. Error	Beta			Lower Bound	Upper Bound
CIMT	(Constant)	0.048	0.003		18.211	<0.001	0.043	0.053
	PCO	0.013	0.003	0.457	4.233	<0.001	0.007	0.019
Model		Unstandardized Coefficients		Standardized Coefficients	t	P value	95.0% Confidence Interval for B
		B	Std. Error	Beta			Lower Bound	Upper Bound
%D change	(Constant)	20.600	2.248		9.165	<0.001	16.115	25.085
	PCO	−10.400-	2.659	−0.428-	−3.911-	<0.001	−15.707-	−5.093-