Prevalence of metabolic syndrome and its components in Chinese women with premature ovarian insufficiency

Figures & data

Table 1. The baseline of indices and comparison between POI women and the control group (Mean ± SD or M (P25, P75)).

	POI group (n = 118)	Control group (n = 151)	T or Z	p
Age, years	31.08 ± 3.99	31.17 ± 3.83	−0.182	.855
BMI, kg/m^2	22.85 ± 3.09	22.16 ± 3.10	1.817	.070
WC, cm	79.44 ± 9.40	77.73 ± 9.04	1.519	.130
WHR	0.816 ± 0.053	0.824 ± 0.052	−1.340	.181
SBP, mmHg	115.72 ± 13.19	114.57 ± 11.07	0.778	.437
DBP, mmHg	74.94 ± 9.00	74.28 ± 8.30	0.620	.536
TG, mmol/L	1.28 ± 1.03	1.01 ± 0.78	2.465	.014
TC, mmol/L	4.77 ± 0.73	4.68 ± 0.79	0.973	.331
HDL-C, mmol/L	1.58 ± 0.51	1.59 ± 0.37	−0.258	.796
LDL-C, mmol/L	2.56 ± 0.62	2.58 ± 0.71	−0.246	.806
FPG, mmol/L	5.13 ± 0.72	5.05 ± 0.49	1.079	.281
FINS, pmol/L	14.58 ± 9.65	10.88 ± 6.10	3.837	<.001
HOMA-IR	2.53 (1.65, 4.79)	2.22 (1.44, 3.14)	−2.633	.008

BMI, body mass index; WC, waist circumference; WHR, waist-hip ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FPG, fasting plasma glucose; FINS, fasting insulin; HOMA-IR, homeostasis model assessment for insulin resistance.

Table 2. Comparison of prevalence of MetS and its components between POI women and the control group (n, %).

	POI group (n = 118)	Control group (n = 151)	χ2	p
MetS	20 (16.9)	17 (11.3)	1.808	.179
WC ≥ 80 cm	47 (39.8)	54 (35.8)	0.468	.494
TG > 1.7 mmol/L	21 (17.8)	14 (9.3)	4.253	.039
HDL-C < 1.3 mmol/L	28 (23.7)	26 (17.2)	1.750	.186
SBP ≥ 130 mmHg or DBP ≥ 85 mmHg	23 (19.5)	22 (14.6)	1.152	.283
FPG ≥ 5.6 mmol/L	20 (16.9)	10 (6.6)	7.129	.008

MetS: metabolic syndrome; WC: waist circumference; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose.

Table 3. Correlation between HOMA-IR and the components of MetS in POI women and control group.

	POI group (n = 118)	Control group (n = 151)
WC, cm	0.449**	0.419**
SBP, mmHg	0.171	0.228**
DBP, mmHg	0.196*	0.262**
TG, mmol/L	0.191*	0.423**
HDL-C, mmol/L	−0.349**	−0.264**
FPG, mmol/L	0.426**	0.530**

*p < .05, **p < .01.

WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; FPG, fasting plasma glucose.

Data availability statement

The authors confirm that the data supporting the findings of this study are available within the article.