Association between anxiety and frailty in postmenopausal women

Figures & data

Figure 1. Flowchart of 390 postmenopausal women with and without frailty.

Table 1. Epidemiological and clinical characteristics of participants according to frailty status.

		Frailty (n = 171)	Non-frailty (n = 219)	p Value*
Age years	<70	48 (28.07)	101 (46.12)	<.001^b
	≥70	123 (71.93)	118 (53.88)
Years since menopause		24.96 ± 11.63	23.77 ± 10.53	.292^a
Height (m)		1.59 ± 0.06	1.58 ± 0.05	.294^a
Weight (kg)		67.68 ± 8.97	69.90 ± 41.67	.493^a
Body mass index (kg/m^2)		26.68 ± 4.01	27.68 ± 16.46	.434^a
Waist circumference (cm)		81.84 ± 8.29	82.56 ± 9.32	.428^a
Marital status	Married/couple	89 (52.04)	133 (60.73)	.220^b
	Separated	30 (17.54)	37 (16.89)
	Single	36 (21.06)	30 (13.70)
	Widow	16 (9.36)	19 (8.68)
Education level	None	17 (9.94)	32 (14.61)	.456^b
	Primary education	83 (48.54)	94 (42.92)
	Secondary education	44 (25.73)	54 (24.66)
	University	27 (15.79)	39 (17.81)
Economic status	High	81 (47.38)	108 (49.31)	.768^b
	Medium	66 (38.59)	77 (35.16)
	Low	24 (14.03)	34 (15.53)
Multimorbidity		137 (80.12)	141 (64.38)	.001^b
Anxiety		119 (69.59)	49 (22.37)	<.001^b
Smoking habit	Ex-Smoker	32 (19.88)	48 (21.91)	.563^b
	Smoker	30 (27.48)	43 (19.64)
	Non-smokers	109 (26.31)	128 (58.45)

Data are expressed as mean ± standard deviation or frequency n (%). *p Value as determined with ^aStudent’s T test or ^bthe chi-square test. Significance differences are highlighted in bold.

Table 2. Factors associated with frailty in postmenopausal women: multivariate analysis by logistic regression.

Factors	OR	95% CI	p Value
Anxiety	8.56	5.30 − 13.82	< .001
Multimorbidity	2.18	1.27 − 3.76	.005
Age	2.73	1.65 − 4.51	< .001

Multimorbidity was established as the presence of two or more diseases. OR: odds ratio; CI: confidence interval.

Data availability statement

All required information regarding the study protocol and the collected data will be made available upon reasonable request to researchers who provide a methodologically sound proposal. Only the analysis required to achieve the aims in the approved proposal will be permitted. Proposals should be directed to [email protected].