The drospirenone only pill as a contraceptive option for breastfeeding women: First data on users’ acceptability and newborn development

Figures & data

Table 1. Women’s characteristics and infant outcome (FAS) and mother BMI.

Parameter	Overall N = 100
Age (years)
N	100
mean (SD)	32.5 (5.4)
median (min–max)	33.0 (20.0–44.0)
Q1–Q3	29.0–35.0
Age (category)
<35 years	69 (69.0%)
> =35 years	31 (31.0%)
Weight (kg)
N	94
mean (SD)	67.6 (13.6)
median (min–max)	66.0 (45.0–114.0)
Q1–Q3	58.2–76.0
Not collected	6
Height (cm)
N	94
mean (SD)	166.8 (5.7)
median (min–max)	166.0 (152.0–180.0)
Q1–Q3	164.0–170.8
Not collected	6
BMI (kg/m^2)
N	94
mean (SD)	24.3 (4.8)
median (min–max)	23.2 (16.3–41.4)
Q1–Q3	20.9–27.1
Not collected	6
BMI categorization[1]
< 20	7 (7.4%)
20–25	53 (56.4%)
25–30	23 (24.5%)
> 30	11 (11.7%)
Not collected	6
Systolic blood pressure (mmHg)
N	87
mean (SD)	118.5 (9.0)
median (min–max)	120.0 (89.0–139.0)
Q1–Q3	112.0–125.0
Not collected	13
Diastolic blood pressure (mmHg)
N	87
mean (SD)	72.1 (7.2)
median (min–max)	71.0 (58.0–89.0)
Q1–Q3	65.5–78.0
Not collected	13
Heart rate (beats/min)
N	75
mean (SD)	78.6 (5.1)
median (min–max)	78.0 (62.0–92.0)
Q1–Q3	76.0–81.0
Not collected	25
Respiratory rate (breath/min)
N	18
mean (SD)	16.1 (1.5)
median (min–max)	16.5 (14.0–18.0)
Q1–Q3	15.0–17.0
Not collected	82
Body temperature (C)
N	56
mean (SD)	36.5 (0.2)
median (min–max)	36.5 (35.9–36.9)
Q1–Q3	36.4–36.7
Not collected	44

Table

Parameter	Overall, N = 98	95% CI[1]	Underweight N = 6	95% CI	Normal weight, N = 52	95% CI	Overweight N = 23	95% CI	Obese N = 11	95% CI
Growth parameters in line with standards
Yes	98 (100.0%)	95.3 –	6 (100.0%)	51.7 –	52 (100.0%)	91.4 –	23 (100.0%)	82.2 –	11 (100.0%)	67.9 –
		100.0		100.0		100.0		100.0		100.0
No	0 (0.0%)		0 (0.0%)		0 (0.0%)		0 (0.0%)		0 (0.0%)

Table 2. Acceptability of DRSP only pill in women who breastfed from 2 to 8 months (FAS).

Parameter	Overall, N = 100	95% CI[1]	Underweight, N = 7	95% CI	Normal weight, N = 53	95% CI	Overweight, N = 23	95% CI	Obese, N = 11	95% CI
Very good	46 (46.0%)		2 (28.6%)		26 (49.1%)		9 (39.1%)		6 (54.5%)
Good	38 (38.0%)		5 (71.4%)		15 (28.3%)		11 (47.8%)		5 (45.5%)
Acceptable	15 (15.0%)		0 (0.0%)		11 (20.8%)		3 (13.0%)		0 (0.0%)
Bad	1 (1.0%)		0 (0.0%)		1 (1.9%)		0 (0.0%)		0 (0.0%)
Very bad	0 (0.0%)		0 (0.0%)		0 (0.0%)		0 (0.0%)		0 (0.0%)
Experience rate with Slinda[3]
Satisfied	84 (84.0%)	75.0–90.3	7 (100.0%)	56.1–100.0	41 (77.4%)	63.5–87.3	20 (87.0%)	65.3–96.6	11 (100.0%)	67.9–100.0
Not satisfied	16 (16.0%)		0 (0.0%)		12 (22.6%)		3 (13.0%)		0 (0.0%)

95% CI calculated using Wilson’s method.

Satisfaction with the use of drospirenone-only pill was determined based on answers to a question “How would you rate your experience with Slinda?” (options "Very good" or "Good" were considered as satisfied while "Acceptable," "Bad" or "Very bad" as unsatisfied).

Table 3. Willingness to continue with the DRSP only pill after breastfeeding (FAS) and type of contraceptive methods used before the pregnancy (FAS).

Parameter	Overall N = 100	95% CI[1]	<35 years N = 69	95% CI	> =35 years N = 31	95% CI
Willingness to take DRSP after breastfeeding
Yes	61 (61.0%)	50.7–70.4%	40 (58.0%)	45.5–69.6%	21 (67.7%)	48.5–82.7%
No	39 (39.0%)		29 (42.0%)		10 (32.3%)
Parameter	Overall, N = 61	95% CI [1]	<35 years old, N = 40	95% CI	≥35 years old, N = 21	95% CI
No contraceptive method
Yes	25 (41.0%)	28.8–54.3%	16 (40.0%)	25.3–56.6%	9 (42.9%)	22.6–65.6%
No	36 (59.0%)		24 (60.0%)		12 (57.1%)
Combined oral contraceptives
Yes	22 (36.1%)	24.5–49.4%	14 (35.0%)	21.1–51.7%	8 (38.1%)	19.0–61.3%
No	39 (63.9%)		26 (65.0%)		13 (61.9%)
Condoms
Yes	19 (31.1%)	20.2–44.4%	14 (35.0%)	21.1–51.7%	5 (23.8%)	9.1–47.5%
No	42 (68.9%)		26 (65.0%)		16 (76.2%)
Vaginal ring
Yes	2 (3.3%)	0.6–12.4%	1 (2.5%)	0.1–14.7%	1 (4.8%)	0.2–25.9%
No	59 (96.7%)		39 (97.5%)		20 (95.2%)
IUD
Yes	0 (0.0%)	0.0–7.4%	0 (0.0%)	0.0–10.9%	0 (0.0%)	0.0–19.2%
No	61 (100.0%)		40 (100.0%)		21 (100.0%)

Availability of data and materials

All data generated or analyzed during this study are included in this published article.