The care status and factors affecting antiretroviral therapy timing for people living with HIV: a retrospective cohort study in Shandong Province, China

Figures & data

Table 1. Status of diagnosis and treatment among newly diagnosed PLWH.

Demographic characteristic	Number of cases diagnosed			Number of cases treated (rate, %)			χ2	P	Cases viral detection (rate, %)			χ2	P	Cases viral suppression (rate, %)			χ2	P
	2018	2019	2020	2018	2019	2020			2018	2019	2020			2018	2019	2020
Gender
Man	2609	2850	2571	1986 (76.12)	2221 (77.93)	2202 (85.65)	201.24	<0.001	1181 (59.47)	1199 (53.98)	1333 (60.54)	0.71	0.40	997 (84.42)	976 (81.40)	902 (67.67)	103.23	<0.001
Woman	244	258	254	182 (74.59)	193 (74.81)	223 (87.80)	34.41	<0.001	114 (62.63)	102 (52.85)	129 (57.85)	0.76	0.38	93 (81.58)	87 (85.29)	86 (66.67)	8.05	0.004
Route of transmission
Homosexual transmission	1950	2142	1963	1537 (78.82)	1707 (79.69)	1722 (87.72)	157.80	<0.001	920 (59.86)	924 (54.13)	1067 (61.96)	1.88	0.17	791 (85.97)	760 (82.25)	710 (66.54)	110.96	<0.001
Heterosexual transmission	873	945	854	613 (70.22)	695 (73.54)	701 (82.08)	61.52	<0.001	361 (58.89)	371 (53.38)	395 (56.35)	0.73	0.39	296 (81.99)	300 (80.86)	278 (70.38)	14.98	<0.001
Injection drug use	20	11	4	11 (55.00)	3 (27.27)	2 (50.00)	0.32	0.57	2 (18.18)	2 (66.67)	0	0.04	0.84	2 (100.00)	1 (50.00)	–	–	–
MTCT	10	10	4	7 (70.00)	9 (90.00)	0 (0.00)	1.56	0.21	5 (71.43)	4 (44.44)	0	–	–	1 (20.00)	2 (50.00)	–	–	–
TOTAL	2853	3108	2825	2168 (75.99)	2414 (77.67)	2425 (85.84)	233.3	<0.001	1296 (59.78)	1301 (53.89)	1462 (60.29)	0.26	0.61	1090 (84.10)	1063 (81.71)	988 (67.57)	110.30	<0.001

Abbreviations: MTCT, mother-to-child transmission.

Table 2. Factors influencing the timeliness of PLWH antiviral therapy.

Variable	Receive ART	NPTI (rate, %)	Univariate analysis		Multivariate analysis
			OR (95%CI)	P	OR (95%CI)	P
Gender
Man	6397	4538 (70.94)	1.00
Woman	610	412 (67.54)	0.88 (0.74∼1.06)	0.17	–	–
Age
≤14	19	7 (36.84)	3.24 (1.27∼8.87)	<0.02	2.99 (0.28∼64.91)	0.37
15∼	1265	848 (67.04)	1.00		1.00
25∼	2302	1605 (69.72)	3.50 (1.37∼9.54)	<0.01	3.35 (0.32∼72.51)	0.33
35∼	1416	1024 (72.32)	4.17 (1.63∼11.40)	0.003	4.25 (0.40∼92.26)	0.24
45∼	2005	1466 (73.12)	4.36 (1.71∼11.91)	0.002	4.75 (0.45∼102.87)	0.21
Census register
This province	6515	4663 (71.57)	1.00		1.00
Other provinces	492	287 (58.33)	0.56 (0.47∼0.68)	<0.001	0.60 (0.50∼0.73)	<0.001
Transmission route
MTCT	16	6 (37.50)	1.00		1.00
Homosexual transmission	4974	3586 (72.09)	3.84 (1.38∼11.48)	<0.01	0.87 (0.04∼11.32)	0.92
Heterosexual transmission	2002	1354 (67.63)	3.18 (1.14∼9.53)	0.03	0.71 (0.03∼9.24)	0.80
Injection drug use	15	4 (26.67)	0.55 (0.11∼2.51)	0.44	0.18 (0.01∼2.97)	0.24
Marriage
Spinsterhood	3080	2143 (69.58)	1.00		1.00
Married with spouse	2751	1959 (71.21)	1.13 (1.01∼1.27)	0.03	1.07 (0.91∼1.25)	0.40
Divorced or widowed	1176	848 (72.11)	1.18 (1.02∼1.38)	0.02	1.04 (0.86∼1.25)	0.69
Ethnicity
Minority	128	73 (57.03)	1.00		1.00
Ethnic Han	6879	4877 (70.90)	1.80 (1.26∼2.57)	0.001	1.37 (0.41∼1.34)	0.10
Sample source
Detained crowd	67	24 (35.82)	1.00		1.00
CTKG	3094	2182 (70.52)	4.11 (2.49∼6.92)	<0.001	3.62 (2.18∼6.16)	<0.001
Medical establishment	3512	2494 (71.01)	4.35 (2.64∼7.33)	<0.001	3.88 (2.33∼6.59)	<0.001
Others	334	250 (74.85)	5.34 (3.07∼9.46)	<0.001	4.86 (2.77∼8.70)	<0.001
Education
Illiteracy or primary school	726	501 (69.01)	1.00		1.00
Junior high school	2160	1484 (68.70)	0.94 (0.78∼1.12)	0.49	0.91 (0.75∼1.11)	0.67
SHTS	1773	1244 (70.16)	1.06 (0.87∼1.27)	0.57	1.09 (0.89∼1.35)	0.40
Junior college or above	2348	1721 (73.30)	1.25 (1.04∼1.50)	0.02	1.39 (1.12∼1.73)	0.002

Abbreviations: NPTI, number of patients treated in time; MTCT, mother-to-child transmission; CTKG, consultation and testing for key groups; and SHTS, senior high school or technical secondary.