https://orcid.org/0000-0001-9746-719X
Figures & data
Figure 1. Temporal evolution first-line regimens and immunologic criteria for treatment initiation based on Brazilian ART guidelines, 2008–2017.
Figure 2. The proposed operational model depicting the relationship between exposure, outcome, and covariates.
Figure 3. Flowchart of the study population, INI Clinical Cohort, Rio de Janeiro, Brazil, 2008–2018.
Figure 4. Percentage of individuals initiating first-line antiretroviral therapy (ART) by type of ART regimen (NNRTI-based regimens [at least 2 NRTIs plus 1 NNRTI], PI-based regimens [at least 2 NRTIs plus 1 PI], INSTI-based regimens [at least 2 NRTIs plus 1 INSTI], and single-tablet regimen [STR, Tenofovir 300 mg, Lamivudine 300 mg plus Efavirenz 600 mg as a single pill]) and year, INI Clinical Cohort, Rio de Janeiro, Brazil, 2008–2018.
![Figure 4. Percentage of individuals initiating first-line antiretroviral therapy (ART) by type of ART regimen (NNRTI-based regimens [at least 2 NRTIs plus 1 NNRTI], PI-based regimens [at least 2 NRTIs plus 1 PI], INSTI-based regimens [at least 2 NRTIs plus 1 INSTI], and single-tablet regimen [STR, Tenofovir 300 mg, Lamivudine 300 mg plus Efavirenz 600 mg as a single pill]) and year, INI Clinical Cohort, Rio de Janeiro, Brazil, 2008–2018.](/cms/asset/dd905572-46ea-4ebd-bc4d-208d91c0f7ee/caic_a_2190954_f0004_ob.jpg)
Table 1. Socio-demographic and clinical characteristics at first-line antiretroviral therapy (ART) initiation, overall, and by first-line ART regimen, INI Clinical Cohort, 2008-2018, Rio de Janeiro, Brazil.
Figure 5. Viral load availability: percentage of individuals with viral load measurements at 6- (left) and 12-months (right) of initiating ART by year of ART initiation, INI Clinical Cohort, Rio de Janeiro, Brazil, 2008–2018.
Figure 6. Viral suppression: percentage of individuals with viral suppresion at 6- (left) and 12-months (right) of initiating ART by year of ART initiation, INI Clinical Cohort, Rio de Janeiro, Brazil, 2008–2018.
Figure 7. Immune response: CD4 cell counts (median and interquartile range) at ART initiation and at 6- and 12-months after initiating ART by ART regimen, INI Clinical Cohort, Rio de Janeiro, Brazil, 2008–2018.
Table 2. Unadjusted and adjusted odds ratio (95% credibility interval) for factors associated with viral suppression at six months, INI Clinical Cohort, 2008-2018, Rio de Janeiro, Brazil.
Table 3. Unadjusted and adjusted odds ratio (95% credibility interval) for factors associated with viral suppression at 12 months, INI Clinical Cohort, 2008-2018, Rio de Janeiro, Brazil.
Supplemental Material
Download MS Word (158 KB)Data availability statement
The final dataset used for the current study is available from the corresponding author on reasonable request.
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