Abstract
A 58‐year‐old man was referred to our department for evaluation and treatment of a therapy‐resistant pyogenic granuloma on his right third digit. This biopsy‐confirmed lesion was unsuccessfully treated with shave excision and base electrocautery on two separate occasions before the patient presented to our clinic. After completing a 14‐week course of twice‐weekly imiquimod 5% topical application, this patient's pyogenic granuloma completely resolved. A satisfactory cosmetic outcome was also achieved, with virtually no scarring.