Bacterial homologs of eukaryotic membrane proteins: the 2-TM-GxN family of Mg²⁺ transporters (Review)

Figures & data

Figure 1.  Panel A shows the CorA homopentamer oriented with the membrane domain at the top. Each monomer is colored independently, and both TM segments are indicated. Panel B shows the homopentamer from the cytosol facing out through the pore (center). The red dots represent the 5 Mg^2 + bound between the α₃-helix of one monomer and the long α₇-helix of an adjacent monomer. The α₇ helices form most of the inner face of the funnel in the cytosol. See ref. [37] for additional details.

Maguire ME. The structure of the CorA magnesium transporter, a divalent cation channel. Curr Opin Struct Biol 2006; 4: 432–438

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