Increased doses of La Sota vaccine increased Newcastle disease antibody response significantly in broiler chickens (Gallus gallus domesticus)

Figures & data

Figure 1. (A). Bursa of broilers on day 3 PV showing no difference in sizes. (B). Bursa of broilers on day 6 PV showing no difference in sizes. (C). Bursa of broilers on day 10 PV. The bursa of the ZD group were bigger in size than the others. ZD = Zero dose SD = Single dose DD = Double dose TD = Triple dose.

Figure 2. (A). ZD bursa showing normal architecture on day 3 PV. H&E Bar = 200 micrometers. (B). ZD bursa showing normal lymphocytic population on day 3 PV. H&E Bar = 50 micrometers. (C). TD bursa showing normal architecture on day 3 PV. H&E Bar = 200 micrometers. (D). TD bursa showing normal lymphocytic population on day 3 PV. H&E Bar = 50 micrometers. (E). ZD bursa showing normal architecture on day 10 PV. H&E Bar = 200 micrometers. (F). ZD bursa showing normal population of lymphocytes on day 10 PV. H&E Bar = 50 microm. (G). TD bursa showing normal architecture on day 10 PV. H&E Bar = 200 microm. (H). TD bursa showing mild depletion of lymphocytes on day10 PV. H&E. Bar = 50 microm. ZD = Zero dose TD = Triple dose.

Figure 3. Newcastle disease haemagglutination inhibition antibody titres in the broilers. A = Zero dose (ZD) group B = Single dose (SD) group. C = Double dose (DD) group D = Triple dose (TD) group.

Table 1. The haemagglutination inhibition Newcastle antibody responses in geometrical mean titres (GMT).

Days post-vaccination	Groups	ZD	SD	DD	TD
0		3	3	3	3
7		0	104	147	128
14		0	294	588	388
21		0	630	1448	1351

ZD = Zero dose SD = Single dose DD = Double dose TD = Triple dose.