1,453
Views
2
CrossRef citations to date
0
Altmetric
Hematological Malignancy Leukemia

Combined chemotherapy for acute promyelocytic leukemia: a meta-analysis

, , , &

Figures & data

Figure 1. Flowchart of study screening and selection process.

Figure 1. Flowchart of study screening and selection process.

Figure 2. A funnel plot showing outcomes of funnel plot symmetry test. Circles inside squares represent possible missing studies as identified by trim and fill method.

Figure 2. A funnel plot showing outcomes of funnel plot symmetry test. Circles inside squares represent possible missing studies as identified by trim and fill method.

Table 1. Important characteristics of the included studies.

Figure 3. Forest graph showing the overall effect size and subgroup-wise effect sizes of complete remission rate following various combined therapies for induction. Abbreviations: ATRA, all-trans retinoic acid; AraC, cytarabine; ATO, arsenic trioxide; BHAC, behenoyl cytosine arabinoside; DNR, daunorubicin; and IDA, idarubicin.

Figure 3. Forest graph showing the overall effect size and subgroup-wise effect sizes of complete remission rate following various combined therapies for induction. Abbreviations: ATRA, all-trans retinoic acid; AraC, cytarabine; ATO, arsenic trioxide; BHAC, behenoyl cytosine arabinoside; DNR, daunorubicin; and IDA, idarubicin.

Figure 4. Forest graph showing the overall effect size and subgroup-wise effect sizes of relapse rate following various combined therapies for induction. Abbreviations: ATRA, all-trans retinoic acid; AraC, cytarabine; ATO, arsenic trioxide; BHAC, behenoyl cytosine arabinoside; DNR, daunorubicin; and IDA, idarubicin.

Figure 4. Forest graph showing the overall effect size and subgroup-wise effect sizes of relapse rate following various combined therapies for induction. Abbreviations: ATRA, all-trans retinoic acid; AraC, cytarabine; ATO, arsenic trioxide; BHAC, behenoyl cytosine arabinoside; DNR, daunorubicin; and IDA, idarubicin.

Figure 5. A scatterplot showing the relationship between year of publication (from 1990 to 2015) and CR rate.

Figure 5. A scatterplot showing the relationship between year of publication (from 1990 to 2015) and CR rate.

Table 2. Prognostic factor analysis for CR and relapse following combinational therapies to APL patients.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.