Relationship between genetic polymorphism of MTHFR C677T and lower extremities deep venous thrombosis

Figures & data

Table 1. Comparison of general information between DVT group and control group.

	Gender
Group	Male	Female	Age
DVT group	45	56	48.5 + 2.1
Control group	57	63	42.5 + 1.9
P-value	>0.05		>0.05

Figure 1. MTHFR genotype analysis electrophoresis map. 1–2: CC genotype; 3–4: CT genotype; 5–10: TT genotype; M: DNA Marker DL2000.

Table 2. C/T frequency distribution of 677th loci in MTHFR between two groups of people.

		Genotype frequency						Allele frequency
		CC		CT		TT		C		T
Group	n	n	%	n	%	n	%	n	%	n	%
DVT group	101	42	41.58	28	25.74	31	32.67*	110	54.46	92	45.54**
Control group	120	70	58.33	26	23.33	24	18.33	168	70.00	72	30.00

Compared with the control group: *P < 0.05, **P < 0.01.

Figure 2. Partial sequencing of C/T mutation at 677th locus of MTHFR. 2.4 Hardy–Weinberg test of genotype distribution in two groups.