Figures & data
Figure 1. Nestin-positive cells in the brain-HPA axis and their role in stress. Under normal conditions, Nestin-positive stem cell/progenitor populations in the hippocampus and adrenal are quiescent. Under stress, differentiation into chromaffin cells (adrenal medulla), steroid-producing cells (adrenal cortex), or oligodendrocytes (hippocampus) is enhanced. Conversely, neurogenesis in the hippocampus and adrenal medulla is decreased under stress.
![Figure 1. Nestin-positive cells in the brain-HPA axis and their role in stress. Under normal conditions, Nestin-positive stem cell/progenitor populations in the hippocampus and adrenal are quiescent. Under stress, differentiation into chromaffin cells (adrenal medulla), steroid-producing cells (adrenal cortex), or oligodendrocytes (hippocampus) is enhanced. Conversely, neurogenesis in the hippocampus and adrenal medulla is decreased under stress.](/cms/asset/4d867ad6-d9de-444b-b2af-955b5627f11b/ists_a_1766441_f0001_c.jpg)