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Special Issue

Are Nestin-positive cells responsive to stress?

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Pages 662-666 | Received 18 Feb 2020, Accepted 03 May 2020, Published online: 22 May 2020

Figures & data

Figure 1. Nestin-positive cells in the brain-HPA axis and their role in stress. Under normal conditions, Nestin-positive stem cell/progenitor populations in the hippocampus and adrenal are quiescent. Under stress, differentiation into chromaffin cells (adrenal medulla), steroid-producing cells (adrenal cortex), or oligodendrocytes (hippocampus) is enhanced. Conversely, neurogenesis in the hippocampus and adrenal medulla is decreased under stress.

Figure 1. Nestin-positive cells in the brain-HPA axis and their role in stress. Under normal conditions, Nestin-positive stem cell/progenitor populations in the hippocampus and adrenal are quiescent. Under stress, differentiation into chromaffin cells (adrenal medulla), steroid-producing cells (adrenal cortex), or oligodendrocytes (hippocampus) is enhanced. Conversely, neurogenesis in the hippocampus and adrenal medulla is decreased under stress.

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