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Abstract
Multi-scale finite element (FE) model is a cost-effective way to analyse stress response of micro-level structures to the changes in loading at macro-level. This study deals with the development of a multi-scale model of a human vertebra and stress changes in the pedicle at high resolution after a gross fracture at the posterior neural arch. Spondylolysis (pars fracture) is a painful condition occurring in the vertebral neural arch and common especially among the athletic young population. The fracture of the pars significantly alters load distribution and load transfer characteristics at the neural arch. Structural changes in the posterior vertebra due to the new loading patterns can trigger secondary complications. Clinical reports have shown the association of pedicle hypertrophy or pedicle fracture with unilateral pars fractures. However, the biomechanical consequences of pars fracture and its effect on the pedicle have never been studied in detail. Therefore, we prepared a multi-scale model of posterior vertebra with continuum laminar complex model combined with micro-FE model of a pedicle section. The results showed that stress at the contralateral pars and pedicle increased after unilateral pars fracture simulation. High-stress regions were found around the outer boundaries of the pedicle. This model and information are helpful in understanding the stress changes in the pedicle and can be used for adaptive remodelling studies.