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Computer Methods in Biomechanics and Biomedical Engineering Volume 22, 2019 - Issue sup1: 44th Congress of the Société de Biomécanique
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Abstract

Transversal elasticity of TIEG1 KO muscle and tendon fibers probed by atomic force microscopy

M. Kammouna Sorbonne University, Université de technologie de Compiègne, CNRS UMR 7338, Compiègne, FranceCorrespondence[email protected]
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,
V. Dupresb Institut Pasteur de Lille, Center of Infection and Immunity of Lille, CNRS UMR 8204, Lille, FranceView further author information
,
J. Landoulsic Pierre and Marie Curie University, Laboratoire de Réactivité de Surface UMR 7197, Paris, FranceView further author information
,
M. Subramaniamd Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, NY, USAView further author information
,
J. Hawsed Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, NY, USAView further author information
&
S. F. Bensamouna Sorbonne University, Université de technologie de Compiègne, CNRS UMR 7338, Compiègne, FranceView further author information
Pages S308-S310 | Published online: 22 May 2020

Figures & data

Figure 1. Elasticity maps (15 x 15 mm) obtained from the AFM protocol for slow (soleus, Sol: A-B) and fast (EDL: C-D) twitch muscle and tendon (E-F) of WT and TIEG1 KO fibers. The muscle and tendon fibers cartographies are represented by different colors which are representative of lower (blue/green) and higher (red/orange) elasticities.

Figure 1. Elasticity maps (15 x 15 mm) obtained from the AFM protocol for slow (soleus, Sol: A-B) and fast (EDL: C-D) twitch muscle and tendon (E-F) of WT and TIEG1 KO fibers. The muscle and tendon fibers cartographies are represented by different colors which are representative of lower (blue/green) and higher (red/orange) elasticities.

Figure 2. Quantification of Young modulus (E) obtained via AFM for WT (NWT_Tendon = 7, NWT_SOL = 7, NWT_EDL = 7) and TIEG1 KO (NKO_Tendon = 7, NKO_SOL = 7, NKO_EDL = 7) fibers. ***p < 0.001 between indicated groups.

Figure 2. Quantification of Young modulus (E) obtained via AFM for WT (NWT_Tendon = 7, NWT_SOL = 7, NWT_EDL = 7) and TIEG1 KO (NKO_Tendon = 7, NKO_SOL = 7, NKO_EDL = 7) fibers. ***p < 0.001 between indicated groups.

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